Anti-LGALS3BP Antibody (CAB6929)
- SKU:
- CAB6929
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LGALS3BP Antibody |
| 抗体コード: | CAB6929 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, HT-29, 293T, HeLa, Mouse liver, Mouse kidney, Mouse lung, Rat brain, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LLLP RSDL AVPS ELAL LKAV DTWS WGER ASHE EVEG LVEK IRFP MMLP EELF ELQF NLSL YWSH EALF QKKT LQAL EFHT VPFQ LLAR YKGL NLTE DTYK PRIY TSPT WSAF VTDS SWSA RKSQ LVYQ SRRG PLVK YSSD YFQA PSDY RYYP YQSF QTPQ HPSF LFQD KRVS WSLV YLPT IQSC WNYG FSCS SDEL PVLG LTKS GGSD RTIA YENK ALML CEGL FVAD VTDF EGWK AAIP SALD TNSS KSTS SFPC PAGH FNGF RTVI RPFY LTNS SGVD |
| 遺伝子ID: | 3959 |
| Uniprot: | Q08380 |
| セルラーロケーション: | Secreted, extracellular matrix, extracellular space |
| 計算された分子量: | 65kDa |
| 観察された分子量: | 75kDa-110kDa |
| 同義語: | LGALS3BP, 90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90 |
| バックグラウンド: | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. |
| UniProt Protein Function: | LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: extracellular matrix; extracellular region; extracellular space Biological Process: cellular defense response; platelet degranulation; signal transduction |
| NCBI Summary: | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q08380 |
| NCBI GenInfo Identifier: | 47115668 |
| NCBI Gene ID: | 3959 |
| NCBI Accession: | Q08380.1 |
| UniProt Secondary Accession: | Q08380,Q7M4S0, Q9UCH8, Q9UCH9, Q9UCI0, |
| UniProt Related Accession: | Q08380 |
| Molecular Weight: | 65kDa |
| NCBI Full Name: | Galectin-3-binding protein |
| NCBI Synonym Full Names: | galectin 3 binding protein |
| NCBI Official Symbol: | LGALS3BP |
| NCBI Official Synonym Symbols: | 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B |
| NCBI Protein Information: | galectin-3-binding protein |
| UniProt Protein Name: | Galectin-3-binding protein |
| UniProt Synonym Protein Names: | Basement membrane autoantigen p105; Lectin galactoside-binding soluble 3-binding protein; Mac-2-binding protein; MAC2BP; Mac-2 BP; Tumor-associated antigen 90K |
| Protein Family: | Galectin-3-binding protein |
| UniProt Gene Name: | LGALS3BP |
 | Western blot analysis of extracts of various cell lines, using LGALS3BP antibody (CAB6929) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of MCF7 cells using LGALS3BP antibody (CAB6929). Blue: DAPI for nuclear staining. |
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