Anti-LETMD1 Antibody (CAB2147)
- SKU:
- CAB2147
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LETMD1 Antibody |
| 抗体コード: | CAB2147 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-360 of human LETMD1 (NP_056231.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-360 of human LETMD1 (NP_056231.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FPRQ LLIR HFWT PKQQ TDFL DIYH AFRK QSHP EIIS YLEK VIPL ISDA GLRW RLTD LCTK IQRG THPA IHDI LALR ECFS NHPL GMNQ LQAL HVKA LSRA MLLT SYLP PPLL RHRL KTHT TVIH QLDK ALAK LGIG QLTA QEVK SACY LRGL NSTH IGED RCRT WLGE WLQI SCSL KEAE LSLL LHNV VLLS TNYL GTRR |
| 遺伝子ID: | 25875 |
| Uniprot: | Q6P1Q0 |
| セルラーロケーション: | Mitochondrion outer membrane, Single-pass membrane protein |
| 計算された分子量: | 11kDa/17kDa/23kDa/35kDa/41kDa/43kDa |
| 観察された分子量: | 41kDa |
| 同義語: | LETMD1, 1110019O13Rik, HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, HCRR-2 |
| バックグラウンド: | This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. |
| UniProt Protein Function: | LETMD1: Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Oncoprotein; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: mitochondrial outer membrane; integral to membrane Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q6P1Q0 |
| NCBI GenInfo Identifier: | 74737159 |
| NCBI Gene ID: | 25875 |
| NCBI Accession: | Q6P1Q0.1 |
| UniProt Related Accession: | Q6P1Q0 |
| Molecular Weight: | |
| NCBI Full Name: | LETM1 domain-containing protein 1 |
| NCBI Synonym Full Names: | LETM1 domain containing 1 |
| NCBI Official Symbol: | LETMD1 |
| NCBI Official Synonym Symbols: | HCCR; HCCR1; HCCR2; HCCR-1; HCCR-2; HCRR-2; SLC55A3; 1110019O13Rik |
| NCBI Protein Information: | LETM1 domain-containing protein 1 |
| UniProt Protein Name: | LETM1 domain-containing protein 1 |
| UniProt Synonym Protein Names: | Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2 |
| Protein Family: | LETM1 domain-containing protein |
| UniProt Gene Name: | LETMD1 |
| UniProt Entry Name: | LTMD1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LETMD1 antibody (CAB2147) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human colon using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Mouse kidney using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Rat testis using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
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