Anti-LDHB Antibody (CAB5131)
- SKU:
- CAB5131
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-LDHB Antibody |
抗体コード: | CAB5131 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IP |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human LDHB |
申し込み: | WB IHC IP |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:50 - 1:200 |
反応性: | Human, Rat |
ポジティブサンプル: | HeLa, Jurkat |
免疫原: | A synthesized peptide derived from human LDHB |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 3945 |
Uniprot: | P07195 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 37kDa |
観察された分子量: | 36KDa |
同義語: | HEL-S-281, LDH-B, LDH-H, LDHBD, TRG-5 |
バックグラウンド: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016] |
NCBI Summary: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016] |
UniProt Code: | P07195 |
NCBI GenInfo Identifier: | 126041 |
NCBI Gene ID: | 3945 |
NCBI Accession: | P07195.2 |
UniProt Related Accession: | P07195 |
Molecular Weight: | ~ 37kDa |
NCBI Full Name: | L-lactate dehydrogenase B chain |
NCBI Synonym Full Names: | lactate dehydrogenase B |
NCBI Official Symbol: | LDHB |
NCBI Official Synonym Symbols: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281 |
NCBI Protein Information: | L-lactate dehydrogenase B chain |
UniProt Protein Name: | L-lactate dehydrogenase B chain |
UniProt Synonym Protein Names: | LDH heart subunit; LDH-H; Renal carcinoma antigen NY-REN-46 |
Protein Family: | L-lactate dehydrogenase |
UniProt Gene Name: | LDHB |
UniProt Entry Name: | LDHB_HUMAN |
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