Anti-LDB2 Antibody (CAB10472)
- SKU:
- CAB10472
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LDB2 Antibody |
| 抗体コード: | CAB10472 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-373 of human LDB2 (NP_001281.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Raji, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-373 of human LDB2 (NP_001281.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LRLC VILE PMQE LMSR HKTY NLSP RDCL KTCL FQKW QRMV APPA EPTR QPTT KRRK RKNS TSST SNSS AGNN ANST GSKK KTTA ANLS LSSQ VPDV MVVG EPTL MGGE FGDE DERL ITRL ENTQ YDAA NGMD DEED FNNS PALG NNSP WNSK PPAT QETK SENP PPQA SQ |
| 遺伝子ID: | 9079 |
| Uniprot: | O43679 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 38kDa/39kDa/42kDa |
| 観察された分子量: | 43kDa |
| 同義語: | LDB2, CLIM1, LDB-2, LDB1 |
| バックグラウンド: | The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | LDB2: Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. Belongs to the LDB family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; Cell development/differentiation Chromosomal Location of Human Ortholog: 4p16 Cellular Component: leading edge; nucleus Molecular Function:LIM domain binding; transcription cofactor activity Biological Process: regulation of cell migration; regulation of kinase activity |
| NCBI Summary: | The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | O43679 |
| NCBI GenInfo Identifier: | 68565371 |
| NCBI Gene ID: | 9079 |
| NCBI Accession: | O43679.1 |
| UniProt Secondary Accession: | O43679,O60619, O75480, |
| UniProt Related Accession: | O43679 |
| Molecular Weight: | 39,740 Da |
| NCBI Full Name: | LIM domain-binding protein 2 |
| NCBI Synonym Full Names: | LIM domain binding 2 |
| NCBI Official Symbol: | LDB2 |
| NCBI Official Synonym Symbols: | LDB1; CLIM1; LDB-2 |
| NCBI Protein Information: | LIM domain-binding protein 2 |
| UniProt Protein Name: | LIM domain-binding protein 2 |
| UniProt Synonym Protein Names: | Carboxyl-terminal LIM domain-binding protein 1; CLIM-1; LIM domain-binding factor CLIM1 |
| Protein Family: | LIM domain-binding protein |
| UniProt Gene Name: | LDB2 |
| UniProt Entry Name: | LDB2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LDB2 antibody (CAB10472) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
View AllClose