Anti-LCMT2 Antibody (CAB17063)
- SKU:
- CAB17063
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-LCMT2 Antibody |
| 抗体コード: | CAB17063 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LCMT2 (NP_055608.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LCMT2 (NP_055608.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MGPR SRER RAGA VQNT NDSS ALSK RSLA ARGY VQDP FAAL LVPG AARR APLI HRGY YVRA RAVR HCVR AFLE QIGA PQAA LRAQ ILSL GAGF DSLY FRLK TAGR LARA AVWE VDFP DVAR RKAE RIGE TPEL CALT GPFE RGEP ASAL CFES ADYC ILGL DLRQ LQRV EEAL GAAG LDAA SPTL LLAE AVLT YLEP ESAA ALIA WAAQ RFPN ALFV VYEQ MRPQ DAFG QFML QHFR QLNS PLHG LERF PDVE AQRR RFLQ AGWT ACGA VDMN EFYH CFLP AEER RRVE NIEP FDEF EEWH |
| 遺伝子ID: | 9836 |
| Uniprot: | O60294 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | LCMT2, PPM2, TYW4 |
| バックグラウンド: | The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). |
| UniProt Protein Function: | LCMT2: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - androgen and estrogen; Other Amino Acids Metabolism - selenoamino acid; Amino Acid Metabolism - tyrosine; Methyltransferase; Amino Acid Metabolism - histidine; EC 2.1.1.290; EC 2.3.1.231 Chromosomal Location of Human Ortholog: 15q15.3 Cellular Component: cytoplasm; cytosol Molecular Function:protein binding; S-adenosylmethionine-dependent methyltransferase activity; tRNA methyltransferase activity Biological Process: tRNA methylation; tRNA modification; wybutosine biosynthetic process |
| NCBI Summary: | The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60294 |
| NCBI GenInfo Identifier: | 47605773 |
| NCBI Gene ID: | 9836 |
| NCBI Accession: | O60294.3 |
| UniProt Secondary Accession: | O60294,Q4JFT6, Q96B55, Q9NR10, |
| UniProt Related Accession: | O60294 |
| Molecular Weight: | 75,602 Da |
| NCBI Full Name: | tRNA wybutosine-synthesizing protein 4 |
| NCBI Synonym Full Names: | leucine carboxyl methyltransferase 2 |
| NCBI Official Symbol: | LCMT2 |
| NCBI Official Synonym Symbols: | PPM2; TYW4 |
| NCBI Protein Information: | tRNA wybutosine-synthesizing protein 4 |
| UniProt Protein Name: | tRNA wybutosine-synthesizing protein 4 |
| UniProt Synonym Protein Names: | Leucine carboxyl methyltransferase 2; tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
| Protein Family: | tRNA wybutosine-synthesizing protein |
| UniProt Gene Name: | LCMT2 |
| UniProt Entry Name: | TYW4_HUMAN |