Anti-LAMP3 Antibody (CAB2895)
- SKU:
- CAB2895
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-LAMP3 Antibody |
| 抗体コード: | CAB2895 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human LAMP3 |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Raji, HT-29, A-549, HeLa |
| 免疫原: | A synthetic peptide of human LAMP3 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 27074 |
| Uniprot: | Q9UQV4 |
| セルラーロケーション: | Cytoplasmic vesicle membrane, Lysosome membrane, Single-pass type I membrane protein |
| 計算された分子量: | 44kDa |
| 観察された分子量: | 75kDa |
| 同義語: | LAMP3, CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 |
| バックグラウンド: | Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]). |
| UniProt Protein Function: | LAMP3: Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. Belongs to the LAMP family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 3q26.3-q27 Cellular Component: lysosomal membrane; integral to membrane Biological Process: cell proliferation; immune system process |
| NCBI Summary: | Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010] |
| UniProt Code: | Q9UQV4 |
| NCBI GenInfo Identifier: | 38455385 |
| NCBI Gene ID: | 27074 |
| NCBI Accession: | NP_055213.2 |
| UniProt Secondary Accession: | Q9UQV4,O94781, Q8NEC8, D3DNS4, |
| UniProt Related Accession: | Q9UQV4 |
| Molecular Weight: | 44,346 Da |
| NCBI Full Name: | lysosome-associated membrane glycoprotein 3 |
| NCBI Synonym Full Names: | lysosomal-associated membrane protein 3 |
| NCBI Official Symbol: | LAMP3 |
| NCBI Official Synonym Symbols: | LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP |
| NCBI Protein Information: | lysosome-associated membrane glycoprotein 3; DC-lysosome-associated membrane glycoprotein |
| UniProt Protein Name: | Lysosome-associated membrane glycoprotein 3 |
| UniProt Synonym Protein Names: | DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403 |
| Protein Family: | Lysosome-associated membrane glycoprotein |
| UniProt Gene Name: | LAMP3 |
| UniProt Entry Name: | LAMP3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LAMP3 antibody (CAB2895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
 | Immunohistochemistry of paraffin-embedded rat brain using LAMP3 antibody (CAB2895) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using LAMP3 antibody (CAB2895) at dilution of 1:200 (40x lens). |
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