Anti-LACRT Antibody (CAB14632)
- SKU:
- CAB14632
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-LACRT Antibody |
| 抗体コード: | CAB14632 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LACRT (NP_150593.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse heart, Mouse thymus |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LACRT (NP_150593.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKFT TLLF LAAV AGAL VYAE DASS DSTG ADPA QEAG TSKP NEEI SGPA EPAS PPET TTTA QETS AAAV QGTA KVTS SRQE LNPL KSIV EKSI LLTE QALA |
| 遺伝子ID: | 90070 |
| Uniprot: | Q9GZZ8 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 14kDa |
| 観察された分子量: | 14kDa |
| 同義語: | LACRT, lacritin |
| バックグラウンド: | The protein encoded by this gene is highly expressed in the lacrimal glands and localized primarily to secretory granules and secretory fluid. It augments lacrimal acinar cell secretion, promotes ductal cell proliferation, and stimulates signaling through tyrosine phosphorylation and release of calcium. |
| UniProt Protein Function: | LACRT: Modulates secretion by lacrimal acinar cells. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12q13.2 Cellular Component: extracellular region; extracellular space; secretory granule Molecular Function:collagen binding; fibronectin binding; growth factor activity; laminin-1 binding; protein N-terminus binding Biological Process: calcineurin-NFAT signaling pathway; calcium-mediated signaling; defense response to bacterium; negative regulation of apoptosis; negative regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of calcium-mediated signaling; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of epithelial cell proliferation involved in wound healing; positive regulation of macroautophagy; positive regulation of NFAT protein import into nucleus; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of secretion; protein amino acid acetylation; protein localization to Golgi apparatus |
| NCBI Summary: | The protein encoded by this gene is highly expressed in the lacrimal glands and localized primarily to secretory granules and secretory fluid. It augments lacrimal acinar cell secretion, promotes ductal cell proliferation, and stimulates signaling through tyrosine phosphorylation and release of calcium. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9GZZ8 |
| NCBI GenInfo Identifier: | 15187164 |
| NCBI Gene ID: | 90070 |
| NCBI Accession: | NP_150593.1 |
| UniProt Related Accession: | Q9GZZ8 |
| Molecular Weight: | |
| NCBI Full Name: | extracellular glycoprotein lacritin |
| NCBI Synonym Full Names: | lacritin |
| NCBI Official Symbol: | LACRT |
| NCBI Protein Information: | extracellular glycoprotein lacritin |
| UniProt Protein Name: | Extracellular glycoprotein lacritin |
| Protein Family: | Extracellular glycoprotein lacritin |
| UniProt Gene Name: | LACRT |
 | Western blot analysis of extracts of various cell lines, using LACRT antibody (CAB14632) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |