Anti-KRT7 Antibody (CAB2574)
- SKU:
- CAB2574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-KRT7 Antibody |
| 抗体コード: | CAB2574 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human KRT7 (NP_005547.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human KRT7 (NP_005547.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ETEL TELQ SQIS DTSV VLSM DNSR SLDL DGII AEVK AQYE EMAK CSRA EAEA WYQT KFET LQAQ AGKH GDDL RNTR NEIS EMNR AIQR LQAE IDNI KNQR AKLE AAIA EAEE RGEL ALKD ARAK QEEL EAAL QRGK QDMA RQLR EYQE LMSV KLAL DIEI ATYR KLLE GEES RLAG DGVG AVNI SVMN STGG SSSG GGIG LTLG GTMG SNAL SFSS SAGP GLLK AYSI RTAS ASRR SARD |
| 遺伝子ID: | 3855 |
| Uniprot: | P08729 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 51kDa |
| 観察された分子量: | 51kDa |
| 同義語: | KRT7, CK7, K2C7, K7, SCL, keratin 7, Keratin |
| バックグラウンド: | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. |
| UniProt Protein Function: | K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 12q13.13 Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus Molecular Function:protein binding; structural molecule activity Biological Process: viral reproduction |
| NCBI Summary: | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P08729 |
| NCBI GenInfo Identifier: | 67782365 |
| NCBI Gene ID: | 3855 |
| NCBI Accession: | NP_005547.3 |
| UniProt Secondary Accession: | P08729,Q92676, Q9BUD8, Q9Y3R7, |
| UniProt Related Accession: | P08729 |
| Molecular Weight: | 51,386 Da |
| NCBI Full Name: | keratin, type II cytoskeletal 7 |
| NCBI Synonym Full Names: | keratin 7 |
| NCBI Official Symbol: | KRT7 |
| NCBI Official Synonym Symbols: | K7; CK7; SCL; K2C7 |
| NCBI Protein Information: | keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7 |
| UniProt Protein Name: | Keratin, type II cytoskeletal 7 |
| UniProt Synonym Protein Names: | Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7 |
| Protein Family: | Keratin |
| UniProt Gene Name: | KRT7 |
| UniProt Entry Name: | K2C7_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using KRT7 antibody (CAB2574). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded human placenta using KRT7 antibody (CAB2574) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of human lung cancer cells using KRT7 antibody (CAB2574) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse bronchus cells using KRT7 antibody (CAB2574) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of rat bronchus cells using KRT7 antibody (CAB2574) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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