Anti-KLRC1 Antibody (CAB1233)
- SKU:
- CAB1233
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-KLRC1 Antibody |
抗体コード: | CAB1233 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_015567.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse testis, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_015567.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RHCG HCPE EWIT YSNS CYYI GKER RTWE ESLL ACTS KNSS LLSI DNEE EMKF LSII SPSS WIGV FRNS SHHP WVTM NGLA FKHE IKDS DNAE LNCA VLQV NRLK SAQC GSSI IYHC KHKL |
遺伝子ID: | 3821 |
Uniprot: | P26715 |
セルラーロケーション: | Membrane, Single-pass type II membrane protein |
計算された分子量: | 24kDa/26kDa |
観察された分子量: | 26kDa |
同義語: | KLRC1, CD159A, NKG2, NKG2A |
バックグラウンド: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
UniProt Protein Function: | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
NCBI Summary: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
UniProt Code: | P26715 |
NCBI GenInfo Identifier: | 317373399 |
NCBI Gene ID: | 3821 |
NCBI Accession: | P26715.2 |
UniProt Related Accession: | P26715 |
Molecular Weight: | 24,250 Da |
NCBI Full Name: | NKG2-A/NKG2-B type II integral membrane protein |
NCBI Synonym Full Names: | killer cell lectin like receptor C1 |
NCBI Official Symbol: | KLRC1 |
NCBI Official Synonym Symbols: | NKG2; NKG2A; CD159A |
NCBI Protein Information: | NKG2-A/NKG2-B type II integral membrane protein |
UniProt Protein Name: | NKG2-A/NKG2-B type II integral membrane protein |
UniProt Synonym Protein Names: | CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD_antigen: CD159a |
UniProt Gene Name: | KLRC1 |
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