Anti-KLHL41 Antibody (CAB15383)
- SKU:
- CAB15383
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-KLHL41 Antibody |
| 抗体コード: | CAB15383 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse heart, Mouse skeletal muscle, Rat skeletal muscle |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MDSQ RELA EELR LYQS TLLQ DGLK DLLD EKKF IDCT LKAG DKSL PCHR LILS ACSP YFRE YFLS EIDE AKKK EVVL DNVD PAIL DLII KYLY SASI DLND GNVQ DIFA LASR FQIP SVFT VCVS YLQK RLAP GNCL AILR LGLL LDCP RLAI SARE FVSD RFVQ ICKE EDFM QLSP QELI SVIS NDSL NVEK EEAV FEAV MKWV RTDK ENRV KNLS EVFD CIRF RLMT EKYF KDHV EKDD IIKS NPDL QKKI KVLK DAFA GKLP EPSK NAAK TGAG EVNG DVGD EDLL PGYL NDIP RHGM |
| 遺伝子ID: | 10324 |
| Uniprot: | O60662 |
| セルラーロケーション: | Cell projection, Cytoplasm, Endoplasmic reticulum membrane, M line, Sarcoplasmic reticulum membrane, cytoskeleton, myofibril, pseudopodium, ruffle, sarcomere |
| 計算された分子量: | 66kDa/68kDa |
| 観察された分子量: | 68kDa |
| 同義語: | KLHL41, KBTBD10, Krp1, SARCOSIN |
| バックグラウンド: | This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. |
| UniProt Protein Function: | KBTBD10: Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Ubiquitin conjugating system; Contractile; Cell adhesion Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: cytoplasm; cytoskeleton; endoplasmic reticulum membrane; M band; nucleus; plasma membrane; sarcoplasmic reticulum membrane Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: myofibril assembly; protein ubiquitination; regulation of myoblast differentiation; sarcomere organization; skeletal muscle fiber development; striated muscle contraction Disease: Nemaline Myopathy 9 |
| NCBI Summary: | This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. [provided by RefSeq, Mar 2015] |
| UniProt Code: | O60662 |
| NCBI GenInfo Identifier: | 14285509 |
| NCBI Gene ID: | 10324 |
| NCBI Accession: | O60662.2 |
| UniProt Secondary Accession: | O60662,Q53R42, |
| UniProt Related Accession: | O60662 |
| Molecular Weight: | 66,866 Da |
| NCBI Full Name: | Kelch-like protein 41 |
| NCBI Synonym Full Names: | kelch like family member 41 |
| NCBI Official Symbol: | KLHL41 |
| NCBI Official Synonym Symbols: | Krp1; KBTBD10; SARCOSIN |
| NCBI Protein Information: | kelch-like protein 41 |
| UniProt Protein Name: | Kelch-like protein 41 |
| UniProt Synonym Protein Names: | Kel-like protein 23; Kelch repeat and BTB domain-containing protein 10; Kelch-related protein 1; Sarcosin |
| Protein Family: | Kelch-like protein |
| UniProt Gene Name: | KLHL41 |
| UniProt Entry Name: | KLH41_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KLHL41 antibody (CAB15383) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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