Anti-KLHL13 Antibody (CAB9989)
- SKU:
- CAB9989
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-KLHL13 Antibody |
| 抗体コード: | CAB9989 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human KLHL13 (NP_277030.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Jurkat, HeLa, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human KLHL13 (NP_277030.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPLK WKTS SPAI WKFP VPVL KTSR STPL SPAY ISLV EEED QHMK LSLG GSEM GLSS HLQS SKAG PTRI FTSN THSS VVLQ GFDQ LRLE GLLC DVTL MPGD TDDA FPVH RVMM ASAS DYFK AMFT GGMK EQDL MCIK LHGV SKVG LRKI IDFI YTAK LSLN MDNL QDTL EAAS FLQI LPVL DFCK VFLI SGVT LDNC VEVG RIAN TYNL TEVD KYVN SFVL KNFP ALLS TGEF LKLP FERL AFVL SSNS LKHC TELE LFKA |
| 遺伝子ID: | 90293 |
| Uniprot: | Q9P2N7 |
| セルラーロケーション: | |
| 計算された分子量: | 69kDa/72kDa/73kDa/74kDa |
| 観察された分子量: | 60kDa |
| 同義語: | KLHL13, BKLHD2 |
| バックグラウンド: | This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | KLHL13: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: Xq23-q24 Molecular Function:ubiquitin-protein ligase activity Biological Process: mitosis; cytokinesis; protein ubiquitination |
| NCBI Summary: | This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9P2N7 |
| NCBI GenInfo Identifier: | 269973869 |
| NCBI Gene ID: | 90293 |
| NCBI Accession: | NP_001161774.1 |
| UniProt Secondary Accession: | Q9P2N7,Q6P2E3, Q96QI7, Q9UDN9, B3KV78, B3KWM7, B7Z3S9 B7Z5P2, B7Z802, D3DWH6, |
| UniProt Related Accession: | Q9P2N7 |
| Molecular Weight: | 74,630 Da |
| NCBI Full Name: | kelch-like protein 13 isoform d |
| NCBI Synonym Full Names: | kelch-like family member 13 |
| NCBI Official Symbol: | KLHL13 |
| NCBI Official Synonym Symbols: | BKLHD2 |
| NCBI Protein Information: | kelch-like protein 13; kelch-like 13; BTB and kelch domain containing 2 |
| UniProt Protein Name: | Kelch-like protein 13 |
| UniProt Synonym Protein Names: | BTB and kelch domain-containing protein 2 |
| Protein Family: | Kelch-like protein |
| UniProt Gene Name: | KLHL13 |
| UniProt Entry Name: | KLH13_HUMAN |
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