Anti-KLF17 Antibody (CAB13743)
- SKU:
- CAB13743
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-KLF17 Antibody |
抗体コード: | CAB13743 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | U-87MG, HepG2, MCF7, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QMLP PQDA HDLG MPPA ESQS LLVL GSQD SLVS QPDS QEGP FLPE QPGP APQT VEKN SRPQ EGTG RRGS SEAR PYCC NYEN CGKA YTKR SHLV SHQR KHTG ERPY SCNW ESCS WSFF RSDE LRRH MRVH TRYR PYKC DQCS REFM RSDH LKQH QKTH RPGP SDPQ ANNN NGEQ DSPP AAGP |
遺伝子ID: | 128209 |
Uniprot: | Q5JT82 |
セルラーロケーション: | Nucleus |
計算された分子量: | 42kDa |
観察された分子量: | 43kDa |
同義語: | KLF17, ZNF393, Zfp393 |
バックグラウンド: |
UniProt Protein Function: | KLF17: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. Belongs to the Sp1 C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding Chromosomal Location of Human Ortholog: 1p34.1 Cellular Component: nucleus Molecular Function:metal ion binding; protein binding; transcription factor activity Biological Process: gamete generation; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent |
UniProt Code: | Q5JT82 |
NCBI GenInfo Identifier: | 74762198 |
NCBI Gene ID: | 128209 |
NCBI Accession: | Q5JT82.1 |
UniProt Secondary Accession: | Q5JT82,Q86VQ7, Q8N805, |
UniProt Related Accession: | Q5JT82 |
Molecular Weight: | 42,577 Da |
NCBI Full Name: | Krueppel-like factor 17 |
NCBI Synonym Full Names: | Kruppel-like factor 17 |
NCBI Official Symbol: | KLF17 |
NCBI Official Synonym Symbols: | ZNF393; Zfp393 |
NCBI Protein Information: | Krueppel-like factor 17 |
UniProt Protein Name: | Krueppel-like factor 17 |
UniProt Synonym Protein Names: | Zinc finger protein 393 |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF17 |
UniProt Entry Name: | KLF17_HUMAN |
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