| UniProt Protein Function: | KLF14: a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2. [provided by RefSeq, Nov 2009] |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 7q32.2 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This intronless gene encodes a member of the Kruppel-like family of transcription factors. The encoded protein functions as a transcriptional co-repressor, and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression. This gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q8TD94 |
| NCBI GenInfo Identifier: | 32129442 |
| NCBI Gene ID: | 136259 |
| NCBI Accession: | Q8TD94.1 |
| UniProt Secondary Accession: | Q8TD94,Q19A42, Q19A43, |
| UniProt Related Accession: | Q8TD94 |
| Molecular Weight: | 33,124 Da |
| NCBI Full Name: | Krueppel-like factor 14 |
| NCBI Synonym Full Names: | Kruppel like factor 14 |
| NCBI Official Symbol: | KLF14 |
| NCBI Official Synonym Symbols: | BTEB5 |
| NCBI Protein Information: | Krueppel-like factor 14 |
| UniProt Protein Name: | Krueppel-like factor 14 |
| UniProt Synonym Protein Names: | Basic transcription element-binding protein 5; BTE-binding protein 5; Transcription factor BTEB5 |
| Protein Family: | Krueppel-like factor |
| UniProt Gene Name: | KLF14 |
