Anti-Kinesin light chain 1 (KLC1) Antibody (CAB19249)
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- SKU:
- CAB19249
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KLC1
- Synonyms:
- KLC
- Synonyms:
- KNS2
- Synonyms:
- KNS2A
- Synonyms:
- kinesin light chain 1
Frequently bought together:
Description
| 抗体名: | Kinesin light chain 1 (KLC1) Rabbit mAb |
| 抗体コード: | CAB19249 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | KLC1, KLC, KNS2, KNS2A, kinesin light chain 1 |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1)). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, MCF7, U-87MG, Mouse brain, Rat brain |
| 免疫原: | Recombinant protein of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1)). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 3831 |
| Uniprot: | Q07866 |
| セルラーロケーション: | Cell projection, Cytoplasm, Cytoplasmic vesicle, cytoskeleton, growth cone |
| 計算された分子量: | 65kDa |
| 観察された分子量: | 65KDa/75KDa |
| UniProt Protein Function: | KLC1: a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 14q32.3 Cellular Component: ciliary rootlet; kinesin complex; microtubule; growth cone; membrane; cell soma; axon; cytoplasmic membrane-bound vesicle; cytosol Molecular Function:tubulin binding; protein binding; motor activity; microtubule motor activity Biological Process: intracellular protein transport; viral reproduction; metabolic process; axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; microtubule-based movement |
| NCBI Summary: | Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q07866 |
| NCBI GenInfo Identifier: | 223590110 |
| NCBI Gene ID: | 3831 |
| NCBI Accession: | Q07866.2 |
| UniProt Secondary Accession: | Q07866,Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ3, Q7RTQ5 Q7RTQ6, Q86SF5, Q86TF5, A6NF62, F8VTM4, |
| UniProt Related Accession: | Q07866 |
| Molecular Weight: | 573 |
| NCBI Full Name: | Kinesin light chain 1 |
| NCBI Synonym Full Names: | kinesin light chain 1 |
| NCBI Official Symbol: | KLC1 |
| NCBI Official Synonym Symbols: | KLC; KNS2; KNS2A |
| NCBI Protein Information: | kinesin light chain 1; kinesin 2 60/70kDa; medulloblastoma antigen MU-MB-2.50 |
| UniProt Protein Name: | Kinesin light chain 1 |
| Protein Family: | Kinesin |
| UniProt Gene Name: | KLC1 |
| UniProt Entry Name: | KLC1_HUMAN |