Anti-KIF11 Antibody (CAB7907)
- SKU:
- CAB7907
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-KIF11 Antibody |
| 抗体コード: | CAB7907 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF IP |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 797-1056 of human KIF11 (NP_004514.2). |
| 申し込み: | WB IF IP |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | Jurkat, NCI-H460, U-251MG, HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 797-1056 of human KIF11 (NP_004514.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SVKH SDKL NGNL EKIS QETE QRCE SLNT RTVY FSEQ WVSS LNER EQEL HNLL EVVS QCCE ASSS DITE KSDG RKAA HEKQ HNIF LDQM TIDE DKLI AQNL ELNE TIKI GLTK LNCF LEQD LKLD IPTG TTPQ RKSY LYPS TLVR TEPR EHLL DQLK RKQP ELLM MLNC SENN KEET IPDV DVEE AVLG QYTE EPLS QEPS VDAG VDCS SIGG VPFF QHKK SHGK DKEN RGIN TLER SKVE ETTE HLVT KSRL PLRA QINL |
| 遺伝子ID: | 3832 |
| Uniprot: | P52732 |
| セルラーロケーション: | Cytoplasm, cytoskeleton, spindle pole |
| 計算された分子量: | 119kDa |
| 観察された分子量: | 130kDa |
| 同義語: | KIF11, EG5, HKSP, KNSL1, MCLMR, TRIP5 |
| バックグラウンド: | This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. |
| UniProt Protein Function: | KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus. |
| UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 10q24.1 Cellular Component: spindle pole; kinesin complex; microtubule; membrane; spindle microtubule; cytoplasm; spindle; cytosol Molecular Function:plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; protein complex binding; microtubule motor activity; protein kinase binding; ATP binding Biological Process: mitosis; mitotic centrosome separation; mitotic spindle organization and biogenesis; cell division; metabolic process; regulation of mitotic centrosome separation; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; spindle organization and biogenesis; microtubule-based movement; chromosome segregation Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation |
| NCBI Summary: | This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P52732 |
| NCBI GenInfo Identifier: | 116242604 |
| NCBI Gene ID: | 3832 |
| NCBI Accession: | P52732.2 |
| UniProt Secondary Accession: | P52732,Q15716, Q5VWX0, A0AV49, B2RMV3, |
| UniProt Related Accession: | P52732 |
| Molecular Weight: | 119,159 Da |
| NCBI Full Name: | Kinesin-like protein KIF11 |
| NCBI Synonym Full Names: | kinesin family member 11 |
| NCBI Official Symbol: | KIF11 |
| NCBI Official Synonym Symbols: | EG5; HKSP; KNSL1; MCLMR; TRIP5 |
| NCBI Protein Information: | kinesin-like protein KIF11; TR-interacting protein 5; TRIP-5; kinesin-like protein 1; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; thyroid receptor-interacting protein 5 |
| UniProt Protein Name: | Kinesin-like protein KIF11 |
| UniProt Synonym Protein Names: | Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5 |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF11 |
| UniProt Entry Name: | KIF11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KIF11 antibody (CAB7907) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of U2OS cells using KIF11 antibody (CAB7907) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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