Anti-KHDRBS3 Antibody (CAB6637)
- SKU:
- CAB6637
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-KHDRBS3 Antibody |
| 抗体コード: | CAB6637 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SW480, BT-474, HepG2, Jurkat |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GSEN ADVP VVRG KPTL RTRG VPAP AITR GRGG VTAR PVGV VVPR GTPT PRGV LSTR GPVS RGRG LLTP RARG VPPT GYRP PPPP PTQE TYGE YDYD DGYG TAYD EQSY DSYD NSYS TPAQ SGAD YYDY GHGL SEET YDSY GQEE WTNS RHKA PSAR TAKG VYRD QPYG RY |
| 遺伝子ID: | 10656 |
| Uniprot: | O75525 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 30kDa/38kDa |
| 観察された分子量: | 39kDa |
| 同義語: | KHDRBS3, Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile |
| バックグラウンド: |
| UniProt Protein Function: | KHDRBS3: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Belongs to the KHDRBS family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q24.2 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; RNA binding; SH3 domain binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spermatogenesis |
| UniProt Code: | O75525 |
| NCBI GenInfo Identifier: | 74735514 |
| NCBI Gene ID: | 10656 |
| NCBI Accession: | O75525.1 |
| UniProt Secondary Accession: | O75525,Q9R226, |
| UniProt Related Accession: | O75525 |
| Molecular Weight: | 346 |
| NCBI Full Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 3 |
| NCBI Synonym Full Names: | KH domain containing, RNA binding, signal transduction associated 3 |
| NCBI Official Symbol: | KHDRBS3 |
| NCBI Official Synonym Symbols: | Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile |
| NCBI Protein Information: | KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein T-Star; sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein, T-STAR |
| UniProt Protein Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 3 |
| UniProt Synonym Protein Names: | RNA-binding protein T-Star; Sam68-like mammalian protein 2; SLM-2; Sam68-like phosphotyrosine protein |
| Protein Family: | Phosphatidylinositol 4,5-bisphosphate-binding protein |
| UniProt Gene Name: | KHDRBS3 |
| UniProt Entry Name: | KHDR3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KHDRBS3 antibody (CAB6637) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunofluorescence analysis of MCF7 cells using KHDRBS3 antibody (CAB6637). |
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