Anti-KDELR1 Antibody (CAB20343)
- SKU:
- CAB20343
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ERD2
- Synonyms:
- HDEL
- Synonyms:
- PM23
- Synonyms:
- ERD2.1
Frequently bought together:
Description
| 抗体名: | KDELR1 Rabbit pAb |
| 抗体コード: | CAB20343 |
| サイズ: | 50uL, 100uL |
| 同義語: | ERD2, HDEL, PM23, ERD2.1 |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 40-100 of human KDELR1 (NP_006792.1). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 40-100 of human KDELR1 (NP_006792.1). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10945 |
| Uniprot: | P24390 |
| 計算された分子量: | 24kDa |
| 観察された分子量: | Refer to figures |
| バックグラウンド: | Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. |
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