Anti-KCNK9 Antibody (CAB12583)
- SKU:
- CAB12583
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-KCNK9 Antibody |
| 抗体コード: | CAB12583 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-374 of human KCNK9 (NP_001269463.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SH-SY5Y, Mouse brain, Mouse large intestine, Mouse pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-374 of human KCNK9 (NP_001269463.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AGNR NSMV IHIP EEPR PSRP RYKA DVPD LQSV CSCT CYRS QDYG GRSV APQN SFSA KLAP HYFH SISY KIEE ISPS TLKN SLFP SPIS SISP GLHS FTDH QRLM KRRK SV |
| 遺伝子ID: | 51305 |
| Uniprot: | Q9NPC2 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 42kDa |
| 観察された分子量: | 42kDa |
| 同義語: | KCNK9, K2p9.1, KT3.2, TASK-3, TASK3 |
| バックグラウンド: | This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | KCNK9: pH-dependent, voltage-insensitive, background potassium channel protein. Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: integral to plasma membrane; plasma membrane; synaptic vesicle Molecular Function:potassium ion leak channel activity; protein heterodimerization activity; protein homodimerization activity; voltage-gated potassium channel activity Biological Process: potassium ion transport; stabilization of membrane potential; synaptic transmission Disease: Birk-barel Mental Retardation Dysmorphism Syndrome |
| NCBI Summary: | This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q9NPC2 |
| NCBI GenInfo Identifier: | 13431426 |
| NCBI Gene ID: | 51305 |
| NCBI Accession: | Q9NPC2.1 |
| UniProt Secondary Accession: | Q9NPC2,Q2M290, Q540F2, |
| UniProt Related Accession: | Q9NPC2 |
| Molecular Weight: | |
| NCBI Full Name: | Potassium channel subfamily K member 9 |
| NCBI Synonym Full Names: | potassium two pore domain channel subfamily K member 9 |
| NCBI Official Symbol: | KCNK9 |
| NCBI Official Synonym Symbols: | KT3.2; TASK3; K2p9.1; TASK-3 |
| NCBI Protein Information: | potassium channel subfamily K member 9 |
| UniProt Protein Name: | Potassium channel subfamily K member 9 |
| UniProt Synonym Protein Names: | Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2 |
| Protein Family: | Potassium channel subfamily |
| UniProt Gene Name: | KCNK9 |
| UniProt Entry Name: | KCNK9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KCNK9 antibody (CAB12583) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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