Anti-KCNH7 Antibody (CAB15923)
- SKU:
- CAB15923
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-KCNH7 Antibody |
| 抗体コード: | CAB15923 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human KCNH7 (NP_775185.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human KCNH7 (NP_775185.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HKNG STFI CNTH IIPV KNQE GVAM MFII NFEY VTDN ENAA TPER VNPI LPIK TVNR KFFG FKFP GLRV LTYR KQSL PQED PDVV VIDS SKHS DDSV AMKH FKSP TKES CSPS EADD TKAL IQPS KCSP LVNI SGPL DHSS PKRQ WDRL YPDM LQSS SQLS HSRS RESL CSIR RASS VHDI EGFG VHPK NIFR DRHA SEGP FNHI KSSL LGST SDSN LNKY STIN KIPQ LTLN FSEV KTEK KNSS PPSS DKT |
| 遺伝子ID: | 90134 |
| Uniprot: | Q9NS40 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 82kDa/135kDa |
| 観察された分子量: | 135kDa |
| 同義語: | KCNH7, ERG3, HERG3, Kv11.3 |
| バックグラウンド: | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. |
| UniProt Protein Function: | Kv11.3: Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.3/KCNH7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 2q24.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:voltage-gated potassium channel activity Biological Process: regulation of membrane potential |
| NCBI Summary: | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NS40 |
| NCBI GenInfo Identifier: | 229462892 |
| NCBI Gene ID: | 90134 |
| NCBI Accession: | Q9NS40.2 |
| UniProt Secondary Accession: | Q9NS40,Q53QU4, Q53TB7, Q53TP9, Q8IV15, |
| UniProt Related Accession: | Q9NS40 |
| Molecular Weight: | 82,904 Da |
| NCBI Full Name: | Potassium voltage-gated channel subfamily H member 7 |
| NCBI Synonym Full Names: | potassium voltage-gated channel subfamily H member 7 |
| NCBI Official Symbol: | KCNH7 |
| NCBI Official Synonym Symbols: | ERG3; HERG3; Kv11.3 |
| NCBI Protein Information: | potassium voltage-gated channel subfamily H member 7 |
| UniProt Protein Name: | Potassium voltage-gated channel subfamily H member 7 |
| UniProt Synonym Protein Names: | Ether-a-go-go-related gene potassium channel 3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; hERG-3; Voltage-gated potassium channel subunit Kv11.3 |
| Protein Family: | Potassium voltage-gated channel subfamily |
| UniProt Gene Name: | KCNH7 |
| UniProt Entry Name: | KCNH7_HUMAN |
 | Western blot analysis of extracts of mouse brain, using KCNH7 antibody (CAB15923) at 1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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