Anti-KCNC1 Antibody (CAB2995)
- SKU:
- CAB2995
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KCNC1
- Synonyms:
- EPM7
- Synonyms:
- KV3.1
- Synonyms:
- KV4
- Synonyms:
- NGK2
Frequently bought together:
Description
| 抗体名: | KCNC1 Rabbit pAb |
| 抗体コード: | CAB2995 |
| サイズ: | 50uL, 100uL |
| 同義語: | KCNC1, EPM7, KV3.1, KV4, NGK2 |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human KCNC1 |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Rat liver |
| 免疫原: | A synthetic peptide of human KCNC1 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 3746 |
| Uniprot: | P48547 |
| セルラーロケーション: | Cell membrane, Membrane, Multi-pass membrane protein |
| 計算された分子量: | 57kDa/65kDa |
| 観察された分子量: | 58KDa |
| UniProt Protein Function: | Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons. |
| NCBI Summary: | This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014] |
| UniProt Code: | P48547 |
| NCBI GenInfo Identifier: | 1352085 |
| NCBI Gene ID: | 3746 |
| NCBI Accession: | P48547.1 |
| UniProt Secondary Accession: | P48547,K4DI87, |
| UniProt Related Accession: | P48547 |
| Molecular Weight: | 65,871 Da |
| NCBI Full Name: | Potassium voltage-gated channel subfamily C member 1 |
| NCBI Synonym Full Names: | potassium voltage-gated channel subfamily C member 1 |
| NCBI Official Symbol: | KCNC1 |
| NCBI Official Synonym Symbols: | KV4; EPM7; NGK2; KV3.1 |
| NCBI Protein Information: | potassium voltage-gated channel subfamily C member 1 |
| UniProt Protein Name: | Potassium voltage-gated channel subfamily C member 1 |
| UniProt Synonym Protein Names: | NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4 |
| Protein Family: | Potassium voltage-gated channel subfamily |
| UniProt Gene Name: | KCNC1 |
| UniProt Entry Name: | KCNC1_HUMAN |
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