Anti-KAZN Antibody (CAB16028)
- SKU:
- CAB16028
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-KAZN Antibody |
| 抗体コード: | CAB16028 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 586-775 of human KAZN (NP_963922.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 586-775 of human KAZN (NP_963922.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YQVN FSRE ALQE RRAR CETQ NIDP VVWT NQRV LKWV RDID LKEY ADNL TNSG VHGA VLVL EPTF NAEA MATA LGIP SGKH ILRR HLAE EMSA VFHP ANST GIRE AERF GTPP GRAS SVTR AGKE ENSS GLKY KAGR LPLG KIGR GFSS KDPD FHDD YGSL QNED CGDD DPQS RLEQ CRLE GYNS LEVT NV |
| 遺伝子ID: | 23254 |
| Uniprot: | Q674X7 |
| セルラーロケーション: | |
| 計算された分子量: | 37kDa/46kDa/86kDa |
| 観察された分子量: | 86kDa |
| 同義語: | KAZN, KAZ, kazrin |
| バックグラウンド: | This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. |
| UniProt Protein Function: | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. |
| NCBI Summary: | This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q674X7 |
| NCBI GenInfo Identifier: | 172044653 |
| NCBI Gene ID: | 23254 |
| NCBI Accession: | Q674X7.2 |
| UniProt Secondary Accession: | Q674X7,Q5TGF1, Q674X4, Q674X6, Q6ZUD1, Q8IYN7, Q8N409 Q9UIL2, Q9UPX4, B0QYQ0, B1AK78, |
| UniProt Related Accession: | Q674X7 |
| Molecular Weight: | 46,250 Da |
| NCBI Full Name: | Kazrin |
| NCBI Synonym Full Names: | kazrin, periplakin interacting protein |
| NCBI Official Symbol: | KAZN |
| NCBI Official Synonym Symbols: | KAZ |
| NCBI Protein Information: | kazrin |
| UniProt Protein Name: | Kazrin |
| Protein Family: | Kazrin |
| UniProt Gene Name: | KAZN |
| UniProt Entry Name: | KAZRN_HUMAN |
 | Western blot analysis of extracts of U-87MG cells, using KAZN antibody (CAB16028) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |