Anti-JPH4 Antibody (CAB10333)
- SKU:
- CAB10333
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-JPH4 Antibody |
抗体コード: | CAB10333 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 405-605 of human JPH4 (NP_115828.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, HT-1080, HepG2, 293T, Mouse liver, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 405-605 of human JPH4 (NP_115828.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AARM AKLI AQDL QPML EAPG RRPR QDSE GSDT EPLD EDSP GVYE NGLT PSEG SPEL PSSP ASSR QPWR PPAC RSPL PPGG DQGP FSSP KAWP EEWG GAGA QAEE LAGY EAED EAGM QGPG PRDG SPLL GGCS DSSG SLRE EEGE DEEP LPPL RAPA GTEP EPIA MLVL RGSS SRGP DAGC LTEE LGEP AATE RPAQ PGAA N |
遺伝子ID: | 84502 |
Uniprot: | Q96JJ6 |
セルラーロケーション: | Cell membrane, Endoplasmic reticulum membrane, Peripheral membrane protein, Single-pass type IV membrane protein |
計算された分子量: | 65kDa |
観察された分子量: | 85kDa |
同義語: | JPH4, JP4, JPHL1 |
バックグラウンド: | This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | JPH4: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory. Belongs to the junctophilin family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 14q11.2 |
NCBI Summary: | This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q96JJ6 |
NCBI GenInfo Identifier: | 34582362 |
NCBI Gene ID: | 84502 |
NCBI Accession: | Q96JJ6.2 |
UniProt Secondary Accession: | Q96JJ6,Q8ND44, Q96DQ0, D3DS53, |
UniProt Related Accession: | Q96JJ6 |
Molecular Weight: | 66kDa |
NCBI Full Name: | Junctophilin-4 |
NCBI Synonym Full Names: | junctophilin 4 |
NCBI Official Symbol: | JPH4 |
NCBI Official Synonym Symbols: | JP4; JPHL1 |
NCBI Protein Information: | junctophilin-4 |
UniProt Protein Name: | Junctophilin-4 |
UniProt Synonym Protein Names: | Junctophilin-like 1 protein |
Protein Family: | Junctophilin |
UniProt Gene Name: | JPH4 |
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