Anti-IVNS1ABP Antibody (CAB4442)
- SKU:
- CAB4442
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IVNS1ABP
- Synonyms:
- FLARA3
- Synonyms:
- HSPC068
- Synonyms:
- KLHL39
- Synonyms:
- ND1
- Synonyms:
- NS-1
- Synonyms:
- NS1-BP
- Synonyms:
- NS1BP
Frequently bought together:
Description
抗体名: | IVNS1ABP Rabbit pAb |
抗体コード: | CAB4442 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | IVNS1ABP, FLARA3, HSPC068, KLHL39, ND1, NS-1, NS1-BP, NS1BP |
申し込み: | WB, IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2). |
申し込み: | WB, IHC |
推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HT-29, Mouse kidney, Mouse lung, Rat spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2). |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MIPN GYLM FEDE NFIE SSVA KLNA LRKS GQFC DVRL QVCG HEML AHRA VLAC CSPY LFEI FNSD SDPH GISH VKFD DLNP EAVE VLLN YAYT AQLK ADKE LVKD VYSA AKKL KMDR VKQV CGDY LLSR MDVT SCIS YRNF ASCM GDSR LLNK VDAY IQEH LLQI SEEE EFLK LPRL KLEV MLED NVCL PSNG KLYT KVIN WVQR SIWE NGDS LEEL MEEV QTLY YSAD HKLL DGNL LDGQ AEVF GSDD DHIQ FVQK KPPR ENGH KQIS SSST GCLS SPNA TVQS PKHE WKIV ASEK TSNN |
遺伝子ID: | 10625 |
Uniprot: | Q9Y6Y0 |
セルラーロケーション: | Cytoplasm, Nucleus, cytoskeleton, nucleoplasm |
計算された分子量: | 71kDa |
観察された分子量: | 72kDa |
UniProt Protein Function: | IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q25.1-q31.1 Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing |
UniProt Code: | Q9Y6Y0 |
NCBI GenInfo Identifier: | 146325015 |
NCBI Gene ID: | 10625 |
NCBI Accession: | Q9Y6Y0.3 |
UniProt Secondary Accession: | Q9Y6Y0,Q1G4T6, Q1G4T7, Q5TF75, Q6NW38, Q7LCG2, Q9NZX0 Q9Y480, A8K8R6, |
UniProt Related Accession: | Q9Y6Y0 |
Molecular Weight: | 642 |
NCBI Full Name: | Influenza virus NS1A-binding protein |
NCBI Synonym Full Names: | influenza virus NS1A binding protein |
NCBI Official Symbol: | IVNS1ABP |
NCBI Official Synonym Symbols: | ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068 |
NCBI Protein Information: | influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3 |
UniProt Protein Name: | Influenza virus NS1A-binding protein |
UniProt Synonym Protein Names: | Aryl hydrocarbon receptor-associated protein 3 |
Protein Family: | Influenza virus NS1A-binding protein |
UniProt Gene Name: | IVNS1ABP |
UniProt Entry Name: | NS1BP_HUMAN |