Anti-ITPKA Antibody (CAB17503)
- SKU:
- CAB17503
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-ITPKA Antibody |
| 抗体コード: | CAB17503 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LLSD SESR SRGN VQLE AGED VGQK NHWQ KIRT MVNL PVIS PFKK RYAW VQLA GHTG SFKA AGTS GLIL KRCS EPER YCLA RLMA DALR GCVP AFHG VVER DGES YLQL QDLL DGFD GPCV LDCK MGVR TYLE EELT KARE RPKL RKDM YKKM LAVD PEAP TEEE HAQR AVTK PRYM QWRE GISS STTL GFRI EGIK KADG SCST DFKT TRSR EQVL RVFE EFVQ GDEE VLRR YLNR LQQI RDTL EVSE FFRR HEVI GSSL LFVH DHCH RAGV WLID FGKT TPLP DGQI LDHR RPWE EGNR EDGY LLGL DNLI GILA SLAE R |
| 遺伝子ID: | 3706 |
| Uniprot: | P23677 |
| セルラーロケーション: | |
| 計算された分子量: | 51kDa |
| 観察された分子量: | 55kDa |
 | Western blot - ITPKA Polyclonal Antibody (CAB17503) |
| 同義語: | IP3-3KA, IP3KA, ITPKA |
| バックグラウンド: | Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011] |
| UniProt Protein Function: | ITPKA: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011] |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; Kinase, lipid; EC 2.7.1.127; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 15q15.1 Cellular Component: cytosol; dendritic spine Molecular Function:ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; inositol trisphosphate 3-kinase activity; Rac GTPase binding Biological Process: actin cytoskeleton organization and biogenesis; inositol metabolic process; inositol phosphate metabolic process; protein amino acid phosphorylation; regulation of synaptic plasticity; signal transduction |
| NCBI Summary: | Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011] |
| UniProt Code: | P23677 |
| NCBI GenInfo Identifier: | 4504789 |
| NCBI Gene ID: | 3706 |
| NCBI Accession: | NP_002211.1 |
| UniProt Secondary Accession: | P23677,Q8TAN3, |
| UniProt Related Accession: | P23677 |
| Molecular Weight: | 51kDa |
| NCBI Full Name: | inositol-trisphosphate 3-kinase A |
| NCBI Synonym Full Names: | inositol-trisphosphate 3-kinase A |
| NCBI Official Symbol: | ITPKA |
| NCBI Official Synonym Symbols: | IP3KA; IP3-3KA |
| NCBI Protein Information: | inositol-trisphosphate 3-kinase A |
| UniProt Protein Name: | Inositol-trisphosphate 3-kinase A |
| UniProt Synonym Protein Names: | Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A |
| Protein Family: | Inositol-trisphosphate 3-kinase |
| UniProt Gene Name: | ITPKA |
| UniProt Entry Name: | IP3KA_HUMAN |