Anti-ITLN1 Antibody (CAB7234)

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SKU:
CAB7234
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-ITLN1 Antibody
抗体コード:CAB7234
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC IF
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 19-313 of human ITLN1 (NP_060095.2).
申し込み:WB IHC IF
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
反応性:Human, Mouse, Rat
ポジティブサンプル:Mouse heart, Rat intestine
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 19-313 of human ITLN1 (NP_060095.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:TDEA NTYF KEWT CSSS PSLP RSCK EIKD ECPS AFDG LYFL RTEN GVIY QTFC DMTS GGGG WTLV ASVH ENDM RGKC TVGD RWSS QQGS KAVY PEGD GNWA NYNT FGSA EAAT SDDY KNPG YYDI QAKD LGIW HVPN KSPM QHWR NSSL LRYR TDTG FLQT LGHN LFGI YQKY PVKY GEGK CWTD NGPV IPVV YDFG DAQK TASY YSPY GQRE FTAG FVQF RVFN NERA ANAL CAGM RVTG CNTE HHCI GGGG YFPE ASPQ QCGD FSGF DWSG YGTH VGYS SSRE ITEA AVLL FYR
遺伝子ID:55600
Uniprot:Q8WWA0
セルラーロケーション:Cell membrane, GPI-anchor, Lipid-anchor, Secreted
計算された分子量:34kDa
観察された分子量:37kDa
同義語:ITLN1, HL-1, HL1, INTL, ITLN, LFR, hIntL, omentin
バックグラウンド:
UniProt Protein Function:ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
UniProt Protein Details:

Protein type:Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: brush border membrane; receptor complex; lipid raft

Molecular Function:carbohydrate binding

Biological Process: positive regulation of glucose import; response to nematode; positive regulation of protein amino acid phosphorylation

UniProt Code:Q8WWA0
NCBI GenInfo Identifier:55976553
NCBI Gene ID:55600
NCBI Accession:Q8WWA0.1
UniProt Secondary Accession:Q8WWA0,Q5IWS4, Q5VYI4, Q6YDJ3, Q9NP67,
UniProt Related Accession:Q8WWA0
Molecular Weight:313
NCBI Full Name:Intelectin-1
NCBI Synonym Full Names:intelectin 1 (galactofuranose binding)
NCBI Official Symbol:ITLN1  
NCBI Official Synonym Symbols:HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin  
NCBI Protein Information:intelectin-1; ITLN-1; endothelial lectin HL-1; galactofuranose-binding lectin; intestinal lactoferrin receptor
UniProt Protein Name:Intelectin-1
UniProt Synonym Protein Names:Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin
Protein Family:Intelectin
UniProt Gene Name:ITLN1  
UniProt Entry Name:ITLN1_HUMAN
Anti-ITLN1 Antibody (CAB7234)Western blot analysis of extracts of various cell lines, using ITLN1 antibody (CAB7234) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-ITLN1 Antibody (CAB7234)Immunohistochemistry of paraffin-embedded mouse intestin using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens).
Anti-ITLN1 Antibody (CAB7234)Immunofluorescence analysis of rat intestine using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Anti-ITLN1 Antibody (CAB7234)Immunofluorescence analysis of mouse colon using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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