Anti-INTS9 Antibody (CAB10480)
- SKU:
- CAB10480
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-INTS9 Antibody |
| 抗体コード: | CAB10480 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 459-658 of human INTS9 (NP_060720.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-251MG, HeLa, Jurkat, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 459-658 of human INTS9 (NP_060720.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KLLK EVQP LHVV CPEQ YTQP PPAQ SHRM DLMI DCQP PAMS YRRA EVLA LPFK RRYE KIEI MPEL ADSL VPME IKPG ISLA TVSA VLHT KDNK HLLQ PPPR PAQP TSGK KRKR VSDD VPDC KVLK PLLS GSIP VEQF VQTL EKHG FSDI KVED TAKG HIVL LQEA ETLI QIEE DSTH IICD NDEM LRVR LRDL VLKF LQKF |
| 遺伝子ID: | 55756 |
| Uniprot: | Q9NV88 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 71kDa/73kDa |
| 観察された分子量: | 74kDa |
| 同義語: | INTS9, CPSF2L, INT9, RC74 |
| バックグラウンド: | This gene encodes a subunit of the Integrator complex. This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing. The encoded protein has similarities to the subunits of the cleavage and polyadenylation specificity factor complex. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | INTS9: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: nucleoplasm; cytoplasm; integrator complex Molecular Function:protein binding Biological Process: snRNA processing |
| NCBI Summary: | This gene encodes a subunit of the Integrator complex. This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing. The encoded protein has similarities to the subunits of the cleavage and polyadenylation specificity factor complex. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010] |
| UniProt Code: | Q9NV88 |
| NCBI GenInfo Identifier: | 119371246 |
| NCBI Gene ID: | 55756 |
| NCBI Accession: | Q9NV88.2 |
| UniProt Related Accession: | Q9NV88 |
| Molecular Weight: | 71kDa; 73kDa |
| NCBI Full Name: | Integrator complex subunit 9 |
| NCBI Synonym Full Names: | integrator complex subunit 9 |
| NCBI Official Symbol: | INTS9 |
| NCBI Official Synonym Symbols: | INT9; RC74; CPSF2L |
| NCBI Protein Information: | integrator complex subunit 9 |
| UniProt Protein Name: | Integrator complex subunit 9 |
| UniProt Synonym Protein Names: | Protein related to CPSF subunits of 74 kDa; RC-74 |
| Protein Family: | Integrator complex |
| UniProt Gene Name: | INTS9 |
| UniProt Entry Name: | INT9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using INTS9 antibody (CAB10480) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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