Anti-INTS5 Antibody (CAB13646)
- SKU:
- CAB13646
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-INTS5 Antibody |
| 抗体コード: | CAB13646 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | MCF7, HT-29 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DVVQ EVQQ VLSE FIRA NPKA WAPV ISAW SIDL MGQL SSTY SGQH QRVP HATG ALNE LLQL WMGC RATR TLMD IYVQ CLSA LIGS CPDA CVDA LLDT SVQH SPHF DWVV AHIG SSFP GTII SRVL SCGL KDFC VHGG AGGG AGSS GGSS SQTP STDP FPGS PAIP AEKR VPKI ASVV GILG HLAS RHGD SIRR ELLR MFHD SLAG GSGG RSGD PSLQ ATVP FLLQ LAVM SPAL LGTV SGEL VDCL KPPA VLSQ LQQH LQGF PREE LDNM LNLA VHLV SQAS G |
| 遺伝子ID: | 80789 |
| Uniprot: | Q6P9B9 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein, Nucleus |
| 計算された分子量: | 107kDa |
| 観察された分子量: | 120kDa |
| 同義語: | INTS5, INT5, KIAA1698 |
| バックグラウンド: | The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex. |
| UniProt Protein Function: | INTS5: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
| UniProt Protein Details: | Protein type:RNA processing; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q12.3 Cellular Component: membrane; integral to membrane; nucleus; integrator complex Molecular Function:protein binding Biological Process: snRNA processing |
| NCBI Summary: | The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex. [provided by RefSeq, Aug 2016] |
| UniProt Code: | Q6P9B9 |
| NCBI GenInfo Identifier: | 74737528 |
| NCBI Gene ID: | 80789 |
| NCBI Accession: | Q6P9B9.1 |
| UniProt Related Accession: | Q6P9B9 |
| Molecular Weight: | 107kDa |
| NCBI Full Name: | Integrator complex subunit 5 |
| NCBI Synonym Full Names: | integrator complex subunit 5 |
| NCBI Official Symbol: | INTS5 |
| NCBI Official Synonym Symbols: | INT5; KIAA1698 |
| NCBI Protein Information: | integrator complex subunit 5 |
| UniProt Protein Name: | Integrator complex subunit 5 |
| Protein Family: | Integrator complex |
| UniProt Gene Name: | INTS5 |
| UniProt Entry Name: | INT5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using INTS5 antibody (CAB13646) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human esophagus using INTS5 antibody (CAB13646) at dilution of 1:100 (40x lens). |
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