Anti-Insulin receptor Antibody (CABP0043)
- SKU:
- CABP0043
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-Insulin receptor Antibody |
抗体コード: | CABP0043 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A phospho specific peptide corresponding to residues surrounding Y1146 of human INSR and Y1131 of human IGF1R |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | A phospho specific peptide corresponding to residues surrounding Y1146 of human INSR and Y1131 of human IGF1R |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 3480/3643 |
Uniprot: | P08069/P06213 |
セルラーロケーション: | |
計算された分子量: | 154kDa/155kDa/156kDa |
観察された分子量: | Refer to Figures |
同義語: | IGF1R/INSR |
バックグラウンド: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |