Anti-INPP5A Antibody (CAB3302)
- SKU:
- CAB3302
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-INPP5A Antibody |
抗体コード: | CAB3302 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse heart, Mouse lung, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TAVL LVTA NVGS LFDD PENL QKNW LREF YQVV HTHK PHFM ALHC QEFG GKNY EASM SHVD KFVK ELLS SDAM KEYN RARV YLDE NYKS QEHF TALG SFYF LHES LKNI YQFD FKAK KYRK VAGK EIYS DTLE STPM LEKE KFPQ DYFP ECKW SRKG FIRT RWCI ADCA FDLV NIHL FHDA SNLV AWET SPS |
遺伝子ID: | 3632 |
Uniprot: | Q14642 |
セルラーロケーション: | Lipid-anchor, Membrane |
計算された分子量: | 47kDa |
観察された分子量: | 40kDa |
同義語: | INPP5A, 5PTASE |
バックグラウンド: | The protein encoded by this gene is a membrane-associated type I inositol 1, 4, 5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. |
UniProt Protein Function: | INPP5A: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type I family. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.56; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 10q26.3 Cellular Component: plasma membrane Molecular Function:PH domain binding; protein binding Biological Process: inositol phosphate metabolic process |
NCBI Summary: | The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14642 |
NCBI GenInfo Identifier: | 3122245 |
NCBI Gene ID: | 3632 |
NCBI Accession: | Q14642.1 |
UniProt Secondary Accession: | Q14642,Q14640, Q5JSF1, D3DXI3, |
UniProt Related Accession: | Q14642 |
Molecular Weight: | 47,820 Da |
NCBI Full Name: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
NCBI Synonym Full Names: | inositol polyphosphate-5-phosphatase A |
NCBI Official Symbol: | INPP5A |
NCBI Official Synonym Symbols: | 5PTASE |
NCBI Protein Information: | type I inositol 1,4,5-trisphosphate 5-phosphatase |
UniProt Protein Name: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
Protein Family: | Type I inositol 1,4,5-trisphosphate 5-phosphatase |
UniProt Gene Name: | INPP5A |
UniProt Entry Name: | I5P1_HUMAN |
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