Anti-INHA Antibody (CAB1734)
- SKU:
- CAB1734
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-INHA Antibody |
| 抗体コード: | CAB1734 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-366 of human INHA (NP_002182.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-366 of human INHA (NP_002182.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CQGL ELAR ELVL AKVR ALFL DALG PPAV TREG GDPG VRRL PRRH ALGG FTHR GSEP EEEE DVSQ AILF PATD ASCE DKSA ARGL AQEA EEGL FRYM FRPS QHTR SRQV TSAQ LWFH TGLD RQGT AASN SSEP LLGL LALS PGGP VAVP MSLG HAPP HWAV LHLA TSAL SLLT HPVL VLLL RCPL CTCS ARPE ATPF LVAH TRTR PPSG GERA RRST PLMS WPWS PSAL RLLQ RPPE EPAA HANC HRVA LNIS FQEL GWER WIVY PPSF IFHY CHGG CGLH IPPN LSLP VPGA PPTP AQPY SLLP GAQP CCAA LPGT MRPL HVRT TSDG GYSF KYET VPNL LTQH CACI |
| 遺伝子ID: | 3623 |
| Uniprot: | P05111 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 40kDa |
| 同義語: | INHA |
| バックグラウンド: | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. |
| UniProt Protein Function: | INHA: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q35 Cellular Component: extracellular region Molecular Function:cytokine activity; growth factor activity; hormone activity; protein binding; receptor binding; transforming growth factor beta receptor binding Biological Process: cell cycle arrest; cell development; cell differentiation; cell surface receptor linked signal transduction; cell-cell signaling; hemoglobin biosynthetic process; negative regulation of B cell differentiation; negative regulation of cell cycle; negative regulation of interferon-gamma biosynthetic process; negative regulation of macrophage differentiation; negative regulation of phosphorylation; positive regulation of follicle-stimulating hormone secretion; regulation of apoptosis; regulation of cell cycle; regulation of cell proliferation; regulation of MAPKKK cascade; response to external stimulus; signal transduction; skeletal development |
| NCBI Summary: | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016] |
| UniProt Code: | P05111 |
| NCBI GenInfo Identifier: | 124274 |
| NCBI Gene ID: | 3623 |
| NCBI Accession: | P05111.1 |
| UniProt Secondary Accession: | P05111,A8K8H5, |
| UniProt Related Accession: | P05111 |
| Molecular Weight: | 39,670 Da |
| NCBI Full Name: | Inhibin alpha chain |
| NCBI Synonym Full Names: | inhibin alpha subunit |
| NCBI Official Symbol: | INHA |
| NCBI Protein Information: | inhibin alpha chain |
| UniProt Protein Name: | Inhibin alpha chain |
| Protein Family: | Inhibin |
| UniProt Gene Name: | INHA |
 | Western blot analysis of extracts of rat testis, using INHA antibody (CAB1734) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded rat brain using INHA antibody (CAB1734) at dilution of 1:200 (40x lens). |
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