Anti-INADL Antibody (CAB12063)
- SKU:
- CAB12063
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-INADL Antibody |
| 抗体コード: | CAB12063 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human INADL (NP_795352.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human INADL (NP_795352.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPEN PATD KLQV LQVL DRLK MKLQ EKGD TSQN EKLS MFYE TLKS PLFN QILT LQQS IKQL KGQL NHIP SDCS ANFD FSRK GLLV FTDG SITN GNVH RPSN |
| 遺伝子ID: | 10207 |
| Uniprot: | Q8NI35 |
| セルラーロケーション: | Apical cell membrane, Cell junction, Cell membrane, Cytoplasm, Peripheral membrane protein, perinuclear region, tight junction |
| 計算された分子量: | 125kDa/167kDa/170kDa/173kDa/196kDa |
| 観察された分子量: | 170kDa |
| 同義語: | PATJ, Cipp, INADL, InaD-like, hINADL |
| バックグラウンド: | This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. |
| UniProt Protein Function: | Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries (PubMed:22006950). |
| NCBI Summary: | This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NI35 |
| NCBI GenInfo Identifier: | 116242542 |
| NCBI Gene ID: | 10207 |
| NCBI Accession: | Q8NI35.3 |
| UniProt Secondary Accession: | Q8NI35,O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7 Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9, |
| UniProt Related Accession: | Q8NI35 |
| Molecular Weight: | 125,231 Da |
| NCBI Full Name: | InaD-like protein |
| NCBI Synonym Full Names: | PATJ, crumbs cell polarity complex component |
| NCBI Official Symbol: | PATJ |
| NCBI Official Synonym Symbols: | Cipp; INADL; hINADL; InaD-like |
| NCBI Protein Information: | inaD-like protein |
| UniProt Protein Name: | InaD-like protein |
| UniProt Synonym Protein Names: | Pals1-associated tight junction protein; Protein associated to tight junctions |
| Protein Family: | Patj |
| UniProt Gene Name: | PATJ |
 | Western blot analysis of extracts of mouse brain, using INADL antibody (CAB12063) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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