Anti-IMPA2 Antibody (CAB10371)
- SKU:
- CAB10371
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-IMPA2 Antibody |
| 抗体コード: | CAB10371 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human IMPA2 (NP_055029.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A375, SW620, Mouse kidney, Mouse brain, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human IMPA2 (NP_055029.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKPS GEDQ AALA AGPW EECF QAAV QLAL RAGQ IIRK ALTE EKRV STKT SAAD LVTE TDHL VEDL IISE LRER FPSH RFIA EEAA ASGA KCVL THSP TWII DPID GTCN FVHR FPTV AVSI GFAV RQEL EFGV IYHC TEER LYTG RRGR GAFC NGQR LRVS GETD LSKA LVLT EIGP KRDP ATLK LFLS NMER LLHA KAHG VRVI GSST LALC HLAS GAAD AYYQ FGLH CWDL AAAT VIIR EAGG IVID TSGG PLDL MACR VVAA STRE MAML IAQA LQTI NYGR DDEK |
| 遺伝子ID: | 3613 |
| Uniprot: | O14732 |
| セルラーロケーション: | |
| 計算された分子量: | 28kDa/31kDa |
| 観察された分子量: | 37kDa |
| 同義語: | IMPA2 |
| バックグラウンド: | This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. |
| UniProt Protein Function: | IMPA2: Can use myo-inositol monophosphates, scylloinositol 1,4- diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'- AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain. Belongs to the inositol monophosphatase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.25; Motility/polarity/chemotaxis; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 18p11.21 Cellular Component: cytoplasm; cytosol Molecular Function:inositol-1(or 4)-monophosphatase activity; protein binding; protein homodimerization activity Biological Process: inositol metabolic process; inositol phosphate dephosphorylation; inositol phosphate metabolic process; phosphate metabolic process; signal transduction |
| NCBI Summary: | This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011] |
| UniProt Code: | O14732 |
| NCBI GenInfo Identifier: | 3914095 |
| NCBI Gene ID: | 3613 |
| NCBI Accession: | O14732.1 |
| UniProt Secondary Accession: | O14732,Q9UJT3, B0YJ29, |
| UniProt Related Accession: | O14732 |
| Molecular Weight: | 31kDa |
| NCBI Full Name: | Inositol monophosphatase 2 |
| NCBI Synonym Full Names: | inositol monophosphatase 2 |
| NCBI Official Symbol: | IMPA2 |
| NCBI Protein Information: | inositol monophosphatase 2 |
| UniProt Protein Name: | Inositol monophosphatase 2 |
| UniProt Synonym Protein Names: | Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2 |
| UniProt Gene Name: | IMPA2 |
 | Western blot analysis of extracts of various cell lines, using IMPA2 antibody (CAB10371) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
View AllClose