Anti-ILKAP Antibody (CAB14305)
- SKU:
- CAB14305
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-ILKAP Antibody |
抗体コード: | CAB14305 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-392 of human ILKAP (NP_110395.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | HeLa, HepG2, Mouse spleen, Mouse testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-392 of human ILKAP (NP_110395.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDLF GDLP EPER SPRP AAGK EAQK GPLL FDDL PPAS STDS GSGG PLLF DDLP PASS GDSG SLAT SISQ MVKT EGKG AKRK TSEE EKNG SEEL VEKK VCKA SSVI FGLK GYVA ERKG EREE MQDA HVIL NDIT EECR PPSS LITR VSYF AVFD GHGG IRAS KFAA QNLH QNLI RKFP KGDV ISVE KTVK RCLL DTFK HTDE EFLK QASS QKPA WKDG STAT CVLA VDNI LYIA NLGD SRAI LCRY NEES QKHA ALSL SKEH NPTQ YEER MRIQ KAGG NVRD GRVL GVLE VSRS IGDG QYKR CGVT SVPD IRRC QLTP NDRF ILLA CDGL FKVF TPEE AVNF ILSC LEDE KIQT REGK SAAD ARYE AACN RLAN KAVQ RGSA DNVT VMVV RIGH |
遺伝子ID: | 80895 |
Uniprot: | Q9H0C8 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 42kDa |
観察された分子量: | 42kDa |
同義語: | ILKAP, ILKAP2, ILKAP3, PP2C-DELTA, PPM1O |
バックグラウンド: | The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. |
UniProt Protein Function: | ILKAP: a protein serine/threonine phosphatase of the PP2C family. Can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
UniProt Protein Details: | Protein type:EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q37.3 Molecular Function:protein binding |
NCBI Summary: | The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H0C8 |
NCBI GenInfo Identifier: | 74752560 |
NCBI Gene ID: | 80895 |
NCBI Accession: | Q9H0C8.1 |
UniProt Secondary Accession: | Q9H0C8,B3KM39, |
UniProt Related Accession: | Q9H0C8 |
Molecular Weight: | 42,907 Da |
NCBI Full Name: | Integrin-linked kinase-associated serine/threonine phosphatase 2C |
NCBI Synonym Full Names: | ILK associated serine/threonine phosphatase |
NCBI Official Symbol: | ILKAP |
NCBI Official Synonym Symbols: | PPM1O; ILKAP2; ILKAP3; PP2C-DELTA |
NCBI Protein Information: | integrin-linked kinase-associated serine/threonine phosphatase 2C |
UniProt Protein Name: | Integrin-linked kinase-associated serine/threonine phosphatase 2C |
Protein Family: | Integrin-linked kinase-associated serine/threonine phosphatase |
UniProt Gene Name: | ILKAP |
UniProt Entry Name: | ILKAP_HUMAN |
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