Anti-IL36A Antibody (CAB8207)
- SKU:
- CAB8207
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | IL36A Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8207 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human IL36A (NP_055255.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HT-29, BT-474, SW480, A-431, HeLa, Mouse skin, Mouse heart, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human IL36A (NP_055255.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEKA LKID TPQQ GSIQ DINH RVWV LQDQ TLIA VPRK DRMS PVTI ALIS CRHV ETLE KDRG NPIY LGLN GLNL CLMC AKVG DQPT LQLK EKDI MDLY NQPE PVKS FLFY HSQS GRNS TFES VAFP GWFI AVSS EGGC PLIL TQEL GKAN TTDF GLTM LF |
| 遺伝子ID: | 27179 |
| Uniprot: | Q9UHA7 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 17kDa |
| 観察された分子量: | 23kDa |
| 同義語: | IL36A, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6 |
| バックグラウンド: | The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. |
| UniProt Protein Function: | IL1F6: Belongs to the IL-1 family. |
| UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 2q12-q14.1 Cellular Component: extracellular region; extracellular space Molecular Function:cytokine activity; interleukin-1 receptor binding Biological Process: cytokine and chemokine mediated signaling pathway |
| NCBI Summary: | The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q9UHA7 |
| NCBI GenInfo Identifier: | 25008601 |
| NCBI Gene ID: | 27179 |
| NCBI Accession: | Q9UHA7.1 |
| UniProt Secondary Accession: | Q9UHA7,Q53SR7, Q5BLR4, Q7RTZ8, B2RAD9, |
| UniProt Related Accession: | Q9UHA7 |
| Molecular Weight: | 17,684 Da |
| NCBI Full Name: | Interleukin-36 alpha |
| NCBI Synonym Full Names: | interleukin 36, alpha |
| NCBI Official Symbol: | IL36A |
| NCBI Official Synonym Symbols: | FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON) |
| NCBI Protein Information: | interleukin-36 alpha |
| UniProt Protein Name: | Interleukin-36 alpha |
| UniProt Synonym Protein Names: | FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL36A |
| UniProt Entry Name: | IL36A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IL36A antibody (CAB8207) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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