Anti-IL-3RA Antibody (CAB3926)
- SKU:
- CAB3926
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | IL3RA Rabbit Polyclonal Antibody |
抗体コード: | CAB3926 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL3RA (NP_002174.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL3RA (NP_002174.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVLL WLTL LLIA LPCL LQTK EDPN PPIT NLRM KAKA QQLT WDLN RNVT DIEC VKDA DYSM PAVN NSYC QFGA ISLC EVTN YTVR VANP PFST WILF PENS |
遺伝子ID: | 3563 |
Uniprot: | P26951 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 34kDa/43kDa |
観察された分子量: | 70kDa |
同義語: | IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra |
バックグラウンド: | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. |
UniProt Protein Function: | IL3RA: This is a receptor for interleukin-3. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3 Cellular Component: plasma membrane; integral to membrane Molecular Function:interleukin-3 receptor activity |
NCBI Summary: | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] |
UniProt Code: | P26951 |
NCBI GenInfo Identifier: | 417184 |
NCBI Gene ID: | 3563 |
NCBI Accession: | P26951.1 |
UniProt Related Accession: | P26951 |
Molecular Weight: | |
NCBI Full Name: | Interleukin-3 receptor subunit alpha |
NCBI Synonym Full Names: | interleukin 3 receptor subunit alpha |
NCBI Official Symbol: | IL3RA |
NCBI Official Synonym Symbols: | IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra |
NCBI Protein Information: | interleukin-3 receptor subunit alpha |
UniProt Protein Name: | Interleukin-3 receptor subunit alpha |
UniProt Synonym Protein Names: | CD_antigen: CD123 |
Protein Family: | Interleukin-3 receptor |
UniProt Gene Name: | IL3RA |
UniProt Entry Name: | IL3RA_HUMAN |
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