Anti-IK Antibody (CAB15280)
- SKU:
- CAB15280
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-IK Antibody |
| 抗体コード: | CAB15280 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human IK (NP_006074.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HeLa, LO2, Mouse brain, Mouse testis, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human IK (NP_006074.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPER DSEP FSNP LAPD GHDV DDPH SFHQ SKLT NEDF RKLL MTPR AAPT SAPP SKSR HHEM PREY NEDE DPAA RRRK KKSY YAKL RQQE IERE RELA EKYR DRAK ERRD GVNK DYEE TELI STTA NYRA VGPT AEAD KSAA EKRR QLIQ ESKF LGGD MEHT HLVK GLDF ALLQ KVRA EIAS KEKE EEEL MEKP QKET KKDE DPEN KIEF KTRL GRNV YRML FKSK AYER NELF LPGR MAYV VDLD DEYA DTDI PTTL IRSK ADCP TMEA QTTL TTND IVIS |
| 遺伝子ID: | 3550 |
| Uniprot: | Q13123 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 65kDa |
| 観察された分子量: | 75kDa |
| 同義語: | IK, CSA2, RED, RER |
| バックグラウンド: | The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. |
| UniProt Protein Function: | Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression (PubMed:22351768, PubMed:24252166). Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint (PubMed:22351768). Required for normal accumulation of SMU1 (PubMed:24945353). |
| NCBI Summary: | The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13123 |
| NCBI GenInfo Identifier: | 125988409 |
| NCBI Gene ID: | 3550 |
| NCBI Accession: | NP_006074.2 |
| UniProt Secondary Accession: | Q13123,Q6IPD8, |
| UniProt Related Accession: | Q13123 |
| Molecular Weight: | 65,602 Da |
| NCBI Full Name: | protein Red |
| NCBI Synonym Full Names: | IK cytokine |
| NCBI Official Symbol: | IK |
| NCBI Official Synonym Symbols: | RED; RER; CSA2 |
| NCBI Protein Information: | protein Red |
| UniProt Protein Name: | Protein Red |
| UniProt Synonym Protein Names: | Cytokine IK |
| Protein Family: | Ikitoxin |
| UniProt Gene Name: | IK |
 | Western blot analysis of extracts of various cell lines, using IK antibody (CAB15280) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 15S. |
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