Anti-IGFALS Antibody (CAB10223)
- SKU:
- CAB10223
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-IGFALS Antibody |
| 抗体コード: | CAB10223 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_004961.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse lung, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_004961.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SCLG RIRP HTFT GLSG LRRL FLKD NGLV GIEE QSLW GLAE LLEL DLTS NQLT HLPH RLFQ GLGK LEYL LLSR NRLA ELPA DALG PLQR AFWL DVSH NRLE ALPN SLLA PLGR LRYL SLRN NSLR TFTP QPPG LERL WLEG NPWD CGCP LKAL RDFA LQNP SAVP RFVQ AICE GDDC QPPA YTYN NITC ASPP EVVG LDLR DLSE AHFA PC |
| 遺伝子ID: | 3483 |
| Uniprot: | P35858 |
| セルラーロケーション: | Secreted, extracellular space |
| 計算された分子量: | 66kDa/70kDa |
| 観察された分子量: | 66kDa/72kDa |
| 同義語: | IGFALS, ACLSD, ALS |
| バックグラウンド: | The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. |
| UniProt Protein Function: | IGFALS: Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: nucleoplasm; extracellular space; extracellular region Molecular Function:insulin-like growth factor binding Biological Process: cellular protein metabolic process; signal transduction; cell adhesion Disease: Acid-labile Subunit Deficiency |
| NCBI Summary: | The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| UniProt Code: | P35858 |
| NCBI GenInfo Identifier: | 4826772 |
| NCBI Gene ID: | 3483 |
| NCBI Accession: | NP_004961 |
| UniProt Related Accession: | P35858 |
| Molecular Weight: | 63kDa |
| NCBI Full Name: | insulin-like growth factor-binding protein complex acid labile subunit isoform 2 |
| NCBI Synonym Full Names: | insulin like growth factor binding protein acid labile subunit |
| NCBI Official Symbol: | IGFALS |
| NCBI Official Synonym Symbols: | ALS; ACLSD |
| NCBI Protein Information: | insulin-like growth factor-binding protein complex acid labile subunit |
| UniProt Protein Name: | Insulin-like growth factor-binding protein complex acid labile subunit |
| Protein Family: | Insulin-like growth factor-binding protein complex acid labile |
| UniProt Gene Name: | IGFALS |
| UniProt Entry Name: | ALS_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IGFALS antibody (CAB10223) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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