Anti-IFT74 Antibody (CAB12672)
- SKU:
- CAB12672
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-IFT74 Antibody |
| 抗体コード: | CAB12672 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-372 of human IFT74 (NP_001092694.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:3000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | DU145, HT-29, A-549, Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-372 of human IFT74 (NP_001092694.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MASN HKSS AARP VSRG GVGL TGRP PSGI RPLS GNIR VATA MPPG TARP GSRG CPIG TGGV LSSQ IKVA HRPV TQQG LTGM KTGT KGPQ RQIL DKSY YLGL LRSK ISEL TTEV NKLQ KGIE MYNQ ENSV YLSY EKRA ETLA VEIK ELQG QLAD YNML VDKL NTNT EMEE VMND YNML KAQN DRET QSLD VIFT ERQA KEKQ IRSV EEEI EQEK QATD DIIK NMSF ENQV KYLE MKTT NEKL LQEL DTLQ QQLD SQNM KKES LEAE IAHS QVKQ EAVL LHEK LYEL ESHR DQMI AEDK SIGS PMEE REKL LKQI KDDN QEIA SMER QLTD TKEK INQF IEEI RQLD MDLE EHQD PTNY GWKI LEKN TGSF KKQV |
| 遺伝子ID: | 80173 |
| Uniprot: | Q96LB3 |
| セルラーロケーション: | Cell projection, Cytoplasmic vesicle, cilium |
| 計算された分子量: | 42kDa/69kDa |
| 観察された分子量: | 80kDa |
| 同義語: | IFT74, BBS20, CCDC2, CMG-1, CMG1 |
| バックグラウンド: |
| UniProt Protein Function: | IFT74: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 9p21.2 Cellular Component: centrosome; cilium Molecular Function:beta-tubulin binding Disease: Bardet-biedl Syndrome 20 |
| NCBI Summary: | This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017] |
| UniProt Code: | Q96LB3 |
| NCBI GenInfo Identifier: | 50400610 |
| NCBI Gene ID: | 80173 |
| NCBI Accession: | Q96LB3.1 |
| UniProt Secondary Accession: | Q96LB3,Q3B789, Q5VY34, Q6PGQ8, Q9H643, Q9H8G7, |
| UniProt Related Accession: | Q96LB3 |
| Molecular Weight: | 69kDa |
| NCBI Full Name: | Intraflagellar transport protein 74 homolog |
| NCBI Synonym Full Names: | intraflagellar transport 74 |
| NCBI Official Symbol: | IFT74 |
| NCBI Official Synonym Symbols: | CMG1; BBS20; CCDC2; CMG-1 |
| NCBI Protein Information: | intraflagellar transport protein 74 homolog |
| UniProt Protein Name: | Intraflagellar transport protein 74 homolog |
| UniProt Synonym Protein Names: | Capillary morphogenesis gene 1 protein; CMG-1; Coiled-coil domain-containing protein 2 |
| Protein Family: | Intraflagellar transport protein |
| UniProt Gene Name: | IFT74 |
 | Western blot analysis of extracts of various cell lines, using IFT74 antibody (CAB12672) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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