Anti-IFT140 Antibody (CAB18664)
- SKU:
- CAB18664
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-IFT140 Antibody |
抗体コード: | CAB18664 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human IFT140. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant protein of human IFT140. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 9742 |
Uniprot: | Q96RY7 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | |
バックグラウンド: |
UniProt Protein Function: | IFT140: Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance. Defects in IFT140 are the cause of Mainzer-Saldino syndrome (MZSDS). MZSDS is a rare autosomal recessive disease characterized by phalangeal cone- shaped epiphyses, chronic renal disease, nearly constant retinal dystrophy, and mild radiographic abnormality of the proximal femur. Occasional features include short stature, cerebellar ataxia, and hepatic fibrosis. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: centrosome; axoneme; photoreceptor connecting cilium Biological Process: skeletal morphogenesis; retina development in camera-type eye; organelle organization and biogenesis; cilium biogenesis Disease: Short-rib Thoracic Dysplasia 9 With Or Without Polydactyly |
NCBI Summary: | This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012] |
UniProt Code: | Q96RY7 |
NCBI GenInfo Identifier: | 41281447 |
NCBI Gene ID: | 9742 |
NCBI Accession: | NP_055529.2 |
UniProt Secondary Accession: | Q96RY7,O60332, Q9UG52, A2A2A8, D3DU75, |
UniProt Related Accession: | Q96RY7 |
Molecular Weight: | Calculated MW: 165kDa Observed MW: 140kDa |
NCBI Full Name: | intraflagellar transport protein 140 homolog |
NCBI Synonym Full Names: | intraflagellar transport 140 |
NCBI Official Symbol: | IFT140 |
NCBI Official Synonym Symbols: | MZSDS; SRTD9; WDTC2; gs114; c305C8.4; c380F5.1 |
NCBI Protein Information: | intraflagellar transport protein 140 homolog; WD and tetratricopeptide repeats protein 2; intraflagellar transport 140 homolog |
UniProt Protein Name: | Intraflagellar transport protein 140 homolog |
UniProt Synonym Protein Names: | WD and tetratricopeptide repeats protein 2 |
Protein Family: | Intraflagellar transport protein |
UniProt Gene Name: | IFT140 |
UniProt Entry Name: | IF140_HUMAN |