Anti-ICE2 Antibody (CAB12871)
- SKU:
- CAB12871
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-ICE2 Antibody |
| 抗体コード: | CAB12871 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human ICE2 (NP_078887.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:1000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human ICE2 (NP_078887.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SRKV PELP LMNL ENSK QPSV SEQL SGPS DSSS WPKS GWPS AFQK PKGR LPYE LQDY VEDT SEYL APQE GNFV YKLF SLQD LLLL VRCS VQRI ETRP RSKK RKKI RRQF PVYV LPKV EYQA CYGV EALT ESEL CRLW TESL L |
| 遺伝子ID: | 79664 |
| Uniprot: | Q659A1 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 8kDa/110kDa |
| 観察された分子量: | 110kDa |
| 同義語: | ICE2, BRCC1, NARG2 |
| バックグラウンド: | This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. |
| UniProt Protein Function: | NARG2: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: Cajal body; cytosol; nuclear body; nucleoplasm; transcription elongation factor complex Molecular Function:protein binding Biological Process: positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter |
| NCBI Summary: | This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. [provided by RefSeq, May 2017] |
| UniProt Code: | Q659A1 |
| NCBI GenInfo Identifier: | 156632596 |
| NCBI Gene ID: | 79664 |
| NCBI Accession: | Q659A1.2 |
| UniProt Secondary Accession: | Q659A1,Q05CT1, Q3B7W6, Q63HP4, Q658Q0, Q68CN8, Q6IPW7 Q6UX23, Q71H65, Q96CY5, Q9HAA2, B2RU08, |
| UniProt Related Accession: | Q659A1 |
| Molecular Weight: | 110kDa |
| NCBI Full Name: | Little elongation complex subunit 2 |
| NCBI Synonym Full Names: | interactor of little elongation complex ELL subunit 2 |
| NCBI Official Symbol: | ICE2 |
| NCBI Official Synonym Symbols: | BRCC1; NARG2 |
| NCBI Protein Information: | little elongation complex subunit 2 |
| UniProt Protein Name: | Little elongation complex subunit 2 |
| UniProt Synonym Protein Names: | Interactor of little elongator complex ELL subunit 2; NMDA receptor-regulated protein 2 |
| Protein Family: | Protein |
| UniProt Gene Name: | ICE2 |
 | Western blot analysis of extracts of mouse brain, using ICE2 antibody (CAB12871) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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