Anti-ICAM2 Antibody (CAB2038)
- SKU:
- CAB2038
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ICAM2 Antibody |
| 抗体コード: | CAB2038 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Jurkat, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KVFE VHVR PKKL AVEP KGSL EVNC STTC NQPE VGGL ETSL DKIL LDEQ AQWK HYLV SNIS HDTV LQCH FTCS GKQE SMNS NVSV YQPP RQVI LTLQ PTLV AVGK SFTI ECRV PTVE PLDS LTLF LFRG NETL HYET FGKA APAP QEAT ATFN STAD REDG HRNF SCLA VLDL MSRG GNIF HKHS APKM LEIY EPVS DSQ |
| 遺伝子ID: | 3384 |
| Uniprot: | P13598 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 30kDa |
| 観察された分子量: | 55kDa |
| 同義語: | ICAM2, CD102 |
| バックグラウンド: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. |
| UniProt Protein Function: | ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod Molecular Function:integrin binding Biological Process: extracellular matrix organization and biogenesis; cell-cell adhesion; regulation of immune response; cell adhesion |
| NCBI Summary: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P13598 |
| NCBI GenInfo Identifier: | 115502404 |
| NCBI Gene ID: | 3384 |
| NCBI Accession: | P13598.2 |
| UniProt Secondary Accession: | P13598,Q14600, |
| UniProt Related Accession: | P13598 |
| Molecular Weight: | 30,654 Da |
| NCBI Full Name: | Intercellular adhesion molecule 2 |
| NCBI Synonym Full Names: | intercellular adhesion molecule 2 |
| NCBI Official Symbol: | ICAM2 |
| NCBI Official Synonym Symbols: | CD102 |
| NCBI Protein Information: | intercellular adhesion molecule 2; ICAM-2 |
| UniProt Protein Name: | Intercellular adhesion molecule 2 |
| UniProt Synonym Protein Names: | CD_antigen: CD102 |
| Protein Family: | Intercellular adhesion molecule |
| UniProt Gene Name: | ICAM2 |
| UniProt Entry Name: | ICAM2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ICAM2 antibody (CAB2038) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). |
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