Anti-HTR1B Antibody (CAB18285)
- SKU:
- CAB18285
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-HTR1B Antibody |
| 抗体コード: | CAB18285 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human HTR1B. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | mouse brain, rat brain |
| 免疫原: | Recombinant protein of human HTR1B. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 3351 |
| Uniprot: | P28222 |
| セルラーロケーション: | |
| 計算された分子量: | 44kDa |
| 観察された分子量: | 44kDa |
 | Western blot - HTR1B Rabbit pAb (CAB18285) |
| 同義語: | S12, 5-HT1B, HTR1D2, HTR1DB, 5-HT-1B, 5-HT1DB, 5-HT-1D-beta, HTR1B |
| バックグラウンド: | The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. |
| UniProt Protein Function: | 5-HT(1B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q13 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:protein binding; serotonin receptor activity Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cAMP biosynthetic process; negative regulation of serotonin secretion; serotonin receptor, adenylate cyclase inhibiting pathway |
| NCBI Summary: | The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015] |
| UniProt Code: | P28222 |
| NCBI GenInfo Identifier: | 112821 |
| NCBI Gene ID: | 3351 |
| NCBI Accession: | P28222.1 |
| UniProt Secondary Accession: | P28222,Q4VAY7, |
| UniProt Related Accession: | P28222 |
| Molecular Weight: | 43,568 Da |
| NCBI Full Name: | 5-hydroxytryptamine receptor 1B |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 1B |
| NCBI Official Symbol: | HTR1B |
| NCBI Official Synonym Symbols: | S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 1B |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 1B |
| UniProt Synonym Protein Names: | S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1B |
| Protein Family: | 5-hydroxytryptamine receptor |
| UniProt Gene Name: | HTR1B |
| UniProt Entry Name: | 5HT1B_HUMAN |