Anti-HSPBP1 Antibody (CAB4574)
- SKU:
- CAB4574
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HSPBP1
- Synonyms:
- FES1
Frequently bought together:
Description
| 抗体名: | HSPBP1 Rabbit pAb |
| 抗体コード: | CAB4574 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | HSPBP1, FES1 |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human HSPBP1 (NP_036399.3). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human HSPBP1 (NP_036399.3). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSDE GSRG SRLP LALP PASQ GCSS GGGG GGSS AGGS GNSR PPRN LQGL LQMA ITAG SEEP DPPP EPMS EERR QWLQ EAMS AAFR GQRE EVEQ MKSC LRVL SQPM PPTA GEAE QAAD QQER EGAL ELLA DLCE NMDN AADF CQLS GMHL LVGR YLEA GAAG LRWR AAQL IGTC SQNV AAIQ EQVL GLGA LRKL LRLL DRDA CDTV RVKA LFAI SCLV REQE AGLL QFLR LDGF SVLM RAMQ QQVQ KLKV KSAF LLQN LLVG HPEH KGTL CSMG MVQQ LVAL VRTE HSPF HEHV LGAL CSLV TDFP QGVR ECRE PELG LEEL LRHR CQLL QQHE EYQE ELEF CEKL LQTC FSSP ADDS MDR |
| 遺伝子ID: | 23640 |
| Uniprot: | Q9NZL4 |
| 計算された分子量: | 28kDa/39kDa/44kDa |
| 観察された分子量: | Refer to figures |
| UniProt Protein Function: | HSPBP1: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.42 Molecular Function:enzyme inhibitor activity; protein binding Biological Process: protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of catalytic activity |
| UniProt Code: | Q9NZL4 |
| NCBI GenInfo Identifier: | 74734730 |
| NCBI Gene ID: | 23640 |
| NCBI Accession: | Q9NZL4.1 |
| UniProt Secondary Accession: | Q9NZL4,O95351, Q6ZNU5, B3KQP0, B4DG11, |
| UniProt Related Accession: | Q9NZL4 |
| Molecular Weight: | 362 |
| NCBI Full Name: | Hsp70-binding protein 1 |
| NCBI Synonym Full Names: | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| NCBI Official Symbol: | HSPBP1 |
| NCBI Official Synonym Symbols: | FES1 |
| NCBI Protein Information: | hsp70-binding protein 1; hsp70 interacting protein; heat shock protein-binding protein 1 |
| UniProt Protein Name: | Hsp70-binding protein 1 |
| UniProt Synonym Protein Names: | Heat shock protein-binding protein 1; Hsp70-binding protein 2; HspBP2; Hsp70-interacting protein 1; Hsp70-interacting protein 2 |
| Protein Family: | Hsp70-binding protein |
| UniProt Gene Name: | HSPBP1 |
| UniProt Entry Name: | HPBP1_HUMAN |