Anti-HOXC8 Antibody (CAB2975)
- SKU:
- CAB2975
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-HOXC8 Antibody |
| 抗体コード: | CAB2975 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human HOXC8 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-251MG |
| 免疫原: | A synthetic peptide of human HOXC8 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 3224 |
| Uniprot: | P31273 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 27kDa |
| 観察された分子量: | 28kDa |
| 同義語: | HOXC8, HOX3, HOX3A |
| バックグラウンド: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. |
| UniProt Protein Function: | HOXC8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: microtubule cytoskeleton; nucleoplasm Molecular Function:sequence-specific DNA binding; transcription factor activity Biological Process: neuron differentiation; anterior/posterior pattern formation; transcription, DNA-dependent; skeletal morphogenesis; negative regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P31273 |
| NCBI GenInfo Identifier: | 13124745 |
| NCBI Gene ID: | 3224 |
| NCBI Accession: | P31273.2 |
| UniProt Related Accession: | P31273 |
| Molecular Weight: | |
| NCBI Full Name: | Homeobox protein Hox-C8 |
| NCBI Synonym Full Names: | homeobox C8 |
| NCBI Official Symbol: | HOXC8 |
| NCBI Official Synonym Symbols: | HOX3; HOX3A |
| NCBI Protein Information: | homeobox protein Hox-C8 |
| UniProt Protein Name: | Homeobox protein Hox-C8 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-3A |
| UniProt Gene Name: | HOXC8 |
| UniProt Entry Name: | HXC8_HUMAN |
 | Western blot analysis of extracts of U-251MG cells, using HOXC8 antibody (CAB2975). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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