Anti-HOXC4 Antibody (CAB13856)
- SKU:
- CAB13856
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-HOXC4 Antibody |
| 抗体コード: | CAB13856 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HOXC4 (NP_055435.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HOXC4 (NP_055435.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PEHS PEYY GRTR ESGF QHHH QELY PPPP PRPS YPER QYSC TSLQ GPGN SRGH GPAQ AGHH HPEK SQSL CEPA PLSG ASAS PSPA PPAC SQPA PDHP SSAA S |
| 遺伝子ID: | 3221 |
| Uniprot: | P09017 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 29kDa |
| 観察された分子量: | 30kDa |
| 同義語: | HOXC4, HOX3, HOX3E, cp19 |
| バックグラウンド: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. |
| UniProt Protein Function: | HOXC4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: nucleus Molecular Function:protein binding |
| NCBI Summary: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09017 |
| NCBI GenInfo Identifier: | 281185468 |
| NCBI Gene ID: | 3221 |
| NCBI Accession: | P09017.2 |
| UniProt Related Accession: | P09017 |
| Molecular Weight: | 29,811 Da |
| NCBI Full Name: | Homeobox protein Hox-C4 |
| NCBI Synonym Full Names: | homeobox C4 |
| NCBI Official Symbol: | HOXC4 |
| NCBI Official Synonym Symbols: | HOX3; cp19; HOX3E |
| NCBI Protein Information: | homeobox protein Hox-C4 |
| UniProt Protein Name: | Homeobox protein Hox-C4 |
| UniProt Synonym Protein Names: | Homeobox protein CP19; Homeobox protein Hox-3E |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXC4 |
| UniProt Entry Name: | HXC4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HOXC4 antibody (CAB13856) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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