Anti-HOMER2 Antibody (CAB16468)
- SKU:
- CAB16468
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-HOMER2 Antibody |
| 抗体コード: | CAB16468 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 144-343 of human HOMER2 (NP_004830.2). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 144-343 of human HOMER2 (NP_004830.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AGPA NTHL KSEN DKLK IALT QSAA NVKK WEIE LQTL RESN ARLT TALQ ESAA SVEQ WKRQ FSIC RDEN DRLR NKID ELEE QCSE INRE KEKN TQLK RRIE ELEA ELRE KETE LKDL RKQS EIIP QLMS ECEY VSEK LEAA ERDN QNLE DKVR SLKT DIEE SKYR QRHL KVEL KSFL EVLD GKID DLHD FRRG LSKL GTDN |
| 遺伝子ID: | 9455 |
| Uniprot: | Q9NSB8 |
| セルラーロケーション: | Cell junction, Cytoplasm, postsynaptic cell membrane, postsynaptic density, synapse |
| 計算された分子量: | 39kDa/40kDa |
| 観察された分子量: |
| 同義語: | HOMER2, ACPD, CPD, DFNA68, HOMER-2, VESL-2 |
| バックグラウンド: | This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. |
| UniProt Protein Function: | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459). Required for normal hearing (PubMed:25816005). |
| NCBI Summary: | This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011] |
| UniProt Code: | Q9NSB8 |
| NCBI GenInfo Identifier: | 46249349 |
| NCBI Gene ID: | 9455 |
| NCBI Accession: | NP_004830.2 |
| UniProt Secondary Accession: | Q9NSB8,O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7, |
| UniProt Related Accession: | Q9NSB8 |
| Molecular Weight: | 39,467 Da |
| NCBI Full Name: | homer protein homolog 2 isoform 1 |
| NCBI Synonym Full Names: | homer scaffold protein 2 |
| NCBI Official Symbol: | HOMER2 |
| NCBI Official Synonym Symbols: | CPD; ACPD; DFNA68; VESL-2; HOMER-2 |
| NCBI Protein Information: | homer protein homolog 2 |
| UniProt Protein Name: | Homer protein homolog 2 |
| UniProt Synonym Protein Names: | Cupidin |
| Protein Family: | Homer protein |
| UniProt Gene Name: | HOMER2 |
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