| UniProt Protein Function: | H1T: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. Belongs to the histone H1/H5 family. |
| UniProt Protein Details: | Protein type:DNA-binding Cellular Component: condensed nuclear chromosome; nucleosome; chromosome; intracellular; nucleus Molecular Function:DNA binding Biological Process: nucleosome assembly; sperm motility; binding of sperm to zona pellucida; multicellular organismal development; spermatogenesis; cell differentiation |
| NCBI Summary: | Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element [provided by RefSeq, Aug 2015] |
| UniProt Code: | Q07133 |
| NCBI GenInfo Identifier: | 112807207 |
| NCBI Gene ID: | 107970 |
| NCBI Accession: | NP_034507.2 |
| UniProt Secondary Accession: | Q07133,Q0VEA3, Q8CGP8, |
| UniProt Related Accession: | Q07133 |
| Molecular Weight: | 21,540 Da |
| NCBI Full Name: | histone H1t |
| NCBI Synonym Full Names: | histone cluster 1, H1t |
| NCBI Official Symbol: | Hist1h1t |
| NCBI Official Synonym Symbols: | H1t; H1.6; H1ft |
| NCBI Protein Information: | histone H1t |
| UniProt Protein Name: | Histone H1t |
| UniProt Synonym Protein Names: | Testicular H1 histone |
| Protein Family: | Histone |
| UniProt Gene Name: | Hist1h1t |
| UniProt Entry Name: | H1T_MOUSE |
