Anti-HERC6 Antibody (CAB18634)
- SKU:
- CAB18634
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-HERC6 Antibody |
| 抗体コード: | CAB18634 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human HERC6. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human HERC6. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 55008 |
| Uniprot: | Q8IVU3 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | |
| バックグラウンド: |
| UniProt Protein Function: | HERC6: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ligase; EC 6.3.2.- Chromosomal Location of Human Ortholog: 4q22.1 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:ligase activity; ubiquitin-protein ligase activity Biological Process: hemopoietic progenitor cell differentiation; protein ubiquitination during ubiquitin-dependent protein catabolic process |
| NCBI Summary: | HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IVU3 |
| NCBI GenInfo Identifier: | 259089405 |
| NCBI Gene ID: | 55008 |
| NCBI Accession: | NP_001158608.1 |
| UniProt Secondary Accession: | Q8IVU3,Q5GC90, Q5GRH3, Q5HYM6, Q5JPB6, Q6PIF4, Q8NAN3 Q9NWS4, B4DIY5, |
| UniProt Related Accession: | Q8IVU3 |
| Molecular Weight: | 32,717 Da |
| NCBI Full Name: | probable E3 ubiquitin-protein ligase HERC6 isoform 2 |
| NCBI Synonym Full Names: | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| NCBI Official Symbol: | HERC6 |
| NCBI Protein Information: | probable E3 ubiquitin-protein ligase HERC6 |
| UniProt Protein Name: | Probable E3 ubiquitin-protein ligase HERC6 |
| UniProt Synonym Protein Names: | HECT domain and RCC1-like domain-containing protein 6 |
| Protein Family: | E3 ISG15--protein ligase |
| UniProt Gene Name: | HERC6 |
| UniProt Entry Name: | HERC6_HUMAN |