Anti-HERC1 Antibody (CAB18601)
- SKU:
- CAB18601
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-HERC1 Antibody |
抗体コード: | CAB18601 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human HERC1. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant protein of human HERC1. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 8925 |
Uniprot: | Q15751 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | |
バックグラウンド: |
UniProt Protein Function: | Involved in membrane trafficking via some guanine nucleotide exchange factor (GEF) activity and its ability to bind clathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDP for free GTP. Binds phosphatidylinositol 4,5-bisphosphate, which is required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. |
NCBI Summary: | This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012] |
UniProt Code: | Q15751 |
NCBI GenInfo Identifier: | 126131099 |
NCBI Gene ID: | 8925 |
NCBI Accession: | NP_003913.3 |
UniProt Secondary Accession: | Q15751,Q8IW65, |
UniProt Related Accession: | Q15751 |
Molecular Weight: | 532,228 Da |
NCBI Full Name: | probable E3 ubiquitin-protein ligase HERC1 |
NCBI Synonym Full Names: | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
NCBI Official Symbol: | HERC1 |
NCBI Official Synonym Symbols: | p532; p619; MDFPMR |
NCBI Protein Information: | probable E3 ubiquitin-protein ligase HERC1 |
UniProt Protein Name: | Probable E3 ubiquitin-protein ligase HERC1 |
UniProt Synonym Protein Names: | HECT domain and RCC1-like domain-containing protein 1; HECT-type E3 ubiquitin transferase HERC1; p532; p619 |
Protein Family: | Probable E3 ubiquitin-protein ligase |
UniProt Gene Name: | HERC1 |