Anti-HBE1 Antibody (CAB3909)
- SKU:
- CAB3909
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-HBE1 Antibody |
| 抗体コード: | CAB3909 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human HBE1 (NP_005321.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | K-562 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human HBE1 (NP_005321.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVHF TAEE KAAV TSLW SKMN VEEA GGEA LGRL LVVY PWTQ RFFD SFGN LSSP SAIL GNPK VKAH GKKV LTSF GDAI KNMD NLKP AFAK LSEL HCDK LHVD PENF KLLG NVMV IILA THFG KEFT PEVQ AAWQ KLVS AVAI ALAH KYH |
| 遺伝子ID: | 3046 |
| Uniprot: | P02100 |
| セルラーロケーション: | |
| 計算された分子量: | 16kDa |
| 観察された分子量: | 12kDa |
| 同義語: | HBE1, HBE |
| バックグラウンド: | The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' |
| UniProt Protein Function: | HBE1: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. Belongs to the globin family. |
| UniProt Protein Details: | Protein type:Carrier Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: hemoglobin complex; cytosol Molecular Function:iron ion binding; heme binding; hemoglobin alpha binding; oxygen binding; oxygen transporter activity Biological Process: oxygen transport; protein heterooligomerization; negative regulation of transcription from RNA polymerase II promoter; blood coagulation |
| NCBI Summary: | The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008] |
| UniProt Code: | P02100 |
| NCBI GenInfo Identifier: | 122726 |
| NCBI Gene ID: | 3046 |
| NCBI Accession: | P02100.2 |
| UniProt Related Accession: | P02100 |
| Molecular Weight: | |
| NCBI Full Name: | Hemoglobin subunit epsilon |
| NCBI Synonym Full Names: | hemoglobin subunit epsilon 1 |
| NCBI Official Symbol: | HBE1 |
| NCBI Official Synonym Symbols: | HBE |
| NCBI Protein Information: | hemoglobin subunit epsilon |
| UniProt Protein Name: | Hemoglobin subunit epsilon |
| UniProt Synonym Protein Names: | Epsilon-globin; Hemoglobin epsilon chain |
| UniProt Gene Name: | HBE1 |
| UniProt Entry Name: | HBE_HUMAN |
 | Western blot analysis of extracts of K-562 cells, using HBE1 antibody (CAB3909) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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